Literature DB >> 17220899

Adenovirus type 11 binding alters the conformation of its receptor CD46.

B David Persson1, Dirk M Reiter, Marko Marttila, Ya-Fang Mei, José M Casasnovas, Niklas Arnberg, Thilo Stehle.   

Abstract

Adenoviruses (Ads) are important human pathogens and valuable gene delivery vehicles. We report here the crystal structure of the species B Ad11 knob complexed with the Ad11-binding region of its receptor CD46. The conformation of bound CD46 differs profoundly from its unbound state, with the bent surface structure straightened into an elongated rod. This mechanism of interaction is likely to be conserved among many pathogens that target CD46 or related molecules.

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Year:  2007        PMID： 17220899     DOI： 10.1038/nsmb1190

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  52 in total

1.  Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3.

Authors:  Beat Amstutz; Michele Gastaldelli; Stefan Kälin; Nicola Imelli; Karin Boucke; Eliane Wandeler; Jason Mercer; Silvio Hemmi; Urs F Greber
Journal:  EMBO J       Date:  2008-03-06       Impact factor: 11.598

2.  Structural variations in species B adenovirus fibers impact CD46 association.

Authors:  Lars Pache; Sangita Venkataraman; Vijay S Reddy; Glen R Nemerow
Journal:  J Virol       Date:  2008-06-04       Impact factor: 5.103

Review 3.  Protein engineering to target complement evasion in cancer.

Authors:  Darrick Carter; André Lieber
Journal:  FEBS Lett       Date:  2013-11-14       Impact factor: 4.124

4.  Structure of the measles virus hemagglutinin bound to the CD46 receptor.

Authors:  César Santiago; María L Celma; Thilo Stehle; José M Casasnovas
Journal:  Nat Struct Mol Biol       Date:  2009-12-13       Impact factor: 15.369

5.  Structure of adenovirus type 21 knob in complex with CD46 reveals key differences in receptor contacts among species B adenoviruses.

Authors:  Karolina Cupelli; Steffen Müller; B David Persson; Marco Jost; Niklas Arnberg; Thilo Stehle
Journal:  J Virol       Date:  2010-01-13       Impact factor: 5.103

6.  Structure-guided insights on the role of NS1 in flavivirus infection.

Authors:  David L Akey; W Clay Brown; Joyce Jose; Richard J Kuhn; Janet L Smith
Journal:  Bioessays       Date:  2015-03-11       Impact factor: 4.345

7.  Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre.

Authors:  Abhimanyu K Singh; Thanh H Nguyen; Márton Z Vidovszky; Balázs Harrach; Mária Benkő; Alan Kirwan; Lokesh Joshi; Michelle Kilcoyne; M Álvaro Berbis; F Javier Cañada; Jesús Jiménez-Barbero; Margarita Menéndez; Sarah S Wilson; Beth A Bromme; Jason G Smith; Mark J van Raaij
Journal:  J Gen Virol       Date:  2018-10-02       Impact factor: 3.891

8.  Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infection.

Authors:  Nathan J Weyand; Christine M Calton; Dustin L Higashi; Kristen J Kanack; Magdalene So
Journal:  J Immunol       Date:  2009-12-16       Impact factor: 5.422

9.  Crystallization and preliminary crystallographic analysis of the measles virus hemagglutinin in complex with the CD46 receptor.

Authors:  César Santiago; Angel Gutiérrez-Rodríguez; Paul A Tucker; Thilo Stehle; José M Casasnovas
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2009-12-25

10.  An arginine switch in the species B adenovirus knob determines high-affinity engagement of cellular receptor CD46.

Authors:  B David Persson; Steffen Müller; Dirk M Reiter; Benedikt B T Schmitt; Marko Marttila; Chris Vanessa Sumowski; Sabine Schweizer; Ulrike Scheu; Christian Ochsenfeld; Niklas Arnberg; Thilo Stehle
Journal:  J Virol       Date:  2008-11-05       Impact factor: 5.103
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