Literature DB >> 17218251

A circadian sleep disorder reveals a complex clock.

Emmanuel Mignot1, Joseph S Takahashi.   

Abstract

Circadian rhythms are established by transcription of clock genes and autoregulatory transcriptional feedback loops. In this issue, Xu et al. (2007) characterize mice expressing a human Per2 mutation identified in patients with familial advanced sleep phase syndrome. Their results reveal that PER2 phosphorylation, by CK1delta and other kinases, is surprisingly complex and has opposite effects on PER2 levels and period length.

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Year:  2007        PMID： 17218251      PMCID： PMC3758472          DOI： 10.1016/j.cell.2006.12.024

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  Post-translational regulation of circadian transcriptional CLOCK(NPAS2)/BMAL1 complex by CRYPTOCHROMES.

Authors:  Roman V Kondratov; Anna A Kondratova; Choogon Lee; Victoria Y Gorbacheva; Mikhail V Chernov; Marina P Antoch
Journal:  Cell Cycle       Date:  2006-04-17       Impact factor: 4.534

2.  An opposite role for tau in circadian rhythms revealed by mathematical modeling.

Authors:  Monica Gallego; Erik J Eide; Margaret F Woolf; David M Virshup; Daniel B Forger
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-03       Impact factor: 11.205

3.  An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.

Authors:  K L Toh; C R Jones; Y He; E J Eide; W A Hinz; D M Virshup; L J Ptácek; Y H Fu
Journal:  Science       Date:  2001-02-09       Impact factor: 47.728

4.  Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome.

Authors:  Ying Xu; Quasar S Padiath; Robert E Shapiro; Christopher R Jones; Susan C Wu; Noriko Saigoh; Kazumasa Saigoh; Louis J Ptácek; Ying-Hui Fu
Journal:  Nature       Date:  2005-03-31       Impact factor: 49.962

5.  BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer.

Authors:  Ilmin Kwon; Jiwon Lee; Seok Hoon Chang; Neon Cheol Jung; Byung Ju Lee; Gi Hoon Son; Kyungjin Kim; Kun Ho Lee
Journal:  Mol Cell Biol       Date:  2006-10       Impact factor: 4.272

6.  Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS).

Authors:  Katja Vanselow; Jens T Vanselow; Pål O Westermark; Silke Reischl; Bert Maier; Thomas Korte; Andreas Herrmann; Hanspeter Herzel; Andreas Schlosser; Achim Kramer
Journal:  Genes Dev       Date:  2006-09-18       Impact factor: 11.361

7.  Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans.

Authors:  C R Jones; S S Campbell; S E Zone; F Cooper; A DeSano; P J Murphy; B Jones; L Czajkowski; L J Ptácek
Journal:  Nat Med       Date:  1999-09       Impact factor: 53.440

8.  Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

Authors:  P L Lowrey; K Shimomura; M P Antoch; S Yamazaki; P D Zemenides; M R Ralph; M Menaker; J S Takahashi
Journal:  Science       Date:  2000-04-21       Impact factor: 47.728

9.  The period length of fibroblast circadian gene expression varies widely among human individuals.

Authors:  Steven A Brown; Fabienne Fleury-Olela; Emi Nagoshi; Conrad Hauser; Cristiana Juge; Christophe A Meier; Rachel Chicheportiche; Jean-Michel Dayer; Urs Albrecht; Ueli Schibler
Journal:  PLoS Biol       Date:  2005-09-27       Impact factor: 8.029
  9 in total
  7 in total

1.  A cross-sectional study on the relationships among the polymorphism of period2 gene, work stress, and insomnia.

Authors:  Ju Li; Chan Huang; Yajia Lan; Yongwei Wang
Journal:  Sleep Breath       Date:  2015-07-15       Impact factor: 2.816

2.  Seed-expressed casein kinase I acts as a positive regulator of the SeFAD2 promoter via phosphorylation of the SebHLH transcription factor.

Authors:  Mi Jung Kim; Young Sam Go; Saet Buyl Lee; Youn Sung Kim; Jeong Sheop Shin; Myung Ki Min; Inhwan Hwang; Mi Chung Suh
Journal:  Plant Mol Biol       Date:  2010-03-28       Impact factor: 4.076

Review 3.  Genetics of sleep and sleep disorders.

Authors:  Amita Sehgal; Emmanuel Mignot
Journal:  Cell       Date:  2011-07-22       Impact factor: 41.582

4.  Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes.

Authors:  Qing-Jun Meng; Elizabeth S Maywood; David A Bechtold; Wei-Qun Lu; Jian Li; Julie E Gibbs; Sandrine M Dupré; Johanna E Chesham; Francis Rajamohan; John Knafels; Blossom Sneed; Laura E Zawadzke; Jeffrey F Ohren; Kevin M Walton; Travis T Wager; Michael H Hastings; Andrew S I Loudon
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-09       Impact factor: 11.205

Review 5.  Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2.

Authors:  Mikyung Kim; June Bryan de la Peña; Jae Hoon Cheong; Hee Jin Kim
Journal:  Biomol Ther (Seoul)       Date:  2018-07-01       Impact factor: 4.634

6.  Epigenetic Control of Circadian Clock Operation during Development.

Authors:  Chengwei Li; Changxia Gong; Shuang Yu; Jianguo Wu; Xiaodong Li
Journal:  Genet Res Int       Date:  2012-03-18

7.  Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins.

Authors:  Qing-Jun Meng; Larisa Logunova; Elizabeth S Maywood; Monica Gallego; Jake Lebiecki; Timothy M Brown; Martin Sládek; Andrei S Semikhodskii; Nicholas R J Glossop; Hugh D Piggins; Johanna E Chesham; David A Bechtold; Seung-Hee Yoo; Joseph S Takahashi; David M Virshup; Raymond P Boot-Handford; Michael H Hastings; Andrew S I Loudon
Journal:  Neuron       Date:  2008-04-10       Impact factor: 17.173
  7 in total

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