Literature DB >> 17217626

Genomic profiling of hormone-naïve lymph node metastases in patients with prostate cancer.

Pamela L Paris1, Matthias D Hofer, Giancarlo Albo, Rainer Kuefer, Juergen E Gschwend, Richard E Hautmann, Jane Fridyland, Jeffrey Simko, Peter R Carroll, Mark A Rubin, Colin Collins.   

Abstract

The progression of organ-confined prostate cancer to metastatic cancer is inevitably fatal. Consequently, identification of structural changes in the genome and associated transcriptional responses that drive this progression is critical to understanding the disease process and the development of biomarkers and therapeutic targets. In this study, whole genome copy number changes in genomes of hormone-naïve lymph node metastases were profiled using array comparative genomic hybridization, and matched primaries were included for a subset. Matched primaries and lymph node metastases showed very similar copy number profiles that are distinct from primary tumors that fail to metastasize.

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Year:  2006        PMID: 17217626      PMCID: PMC1783716          DOI: 10.1593/neo.06421

Source DB:  PubMed          Journal:  Neoplasia        ISSN: 1476-5586            Impact factor:   5.715


  20 in total

1.  Two putative tumor suppressor genes on chromosome arm 8p may play different roles in prostate cancer.

Authors:  K Oba; H Matsuyama; S Yoshihiro; F Kishi; M Takahashi; M Tsukamoto; M Kinjo; K Sagiyama; K Naito
Journal:  Cancer Genet Cytogenet       Date:  2001-01-01

2.  Loss of p53 and c-myc overrepresentation in stage T(2-3)N(1-3)M(0) prostate cancer are potential markers for cancer progression.

Authors:  Junqi Qian; Kiyoshi Hirasawa; David G Bostwick; Erik J Bergstralh; Jeff M Slezak; Kari L Anderl; Thomas J Borell; Michael M Lieber; Robert B Jenkins
Journal:  Mod Pathol       Date:  2002-01       Impact factor: 7.842

3.  Determination of a minimal deletion interval on chromosome band 8p21 in sporadic prostate cancer.

Authors:  Jennifer I Swalwell; Cathy D Vocke; Youfeng Yang; Jonathan R Walker; Lynette Grouse; Stuart H Myers; John W Gillespie; David G Bostwick; Paul H Duray; W Marston Linehan; Michael R Emmert-Buck
Journal:  Genes Chromosomes Cancer       Date:  2002-02       Impact factor: 5.006

4.  Preliminary evaluation of prostate cancer metastatic risk biomarkers.

Authors:  P L Paris; V Weinberg; J Simko; A Andaya; G Albo; M A Rubin; P R Carroll; C Collins
Journal:  Int J Biol Markers       Date:  2005 Jul-Sep       Impact factor: 2.659

5.  Identification of the messenger RNA for human cutaneous fatty acid-binding protein as a metastasis inducer.

Authors:  C Jing; C Beesley; C S Foster; P S Rudland; H Fujii; T Ono; H Chen; P H Smith; Y Ke
Journal:  Cancer Res       Date:  2000-05-01       Impact factor: 12.701

6.  Human cutaneous fatty acid-binding protein induces metastasis by up-regulating the expression of vascular endothelial growth factor gene in rat Rama 37 model cells.

Authors:  C Jing; C Beesley; C S Foster; H Chen; P S Rudland; D C West; H Fujii; P H Smith; Y Ke
Journal:  Cancer Res       Date:  2001-06-01       Impact factor: 12.701

7.  High-resolution analysis of paraffin-embedded and formalin-fixed prostate tumors using comparative genomic hybridization to genomic microarrays.

Authors:  Pamela L Paris; Donna G Albertson; Janneke C Alers; Armann Andaya; Peter Carroll; Jane Fridlyand; Ajay N Jain; Sherwin Kamkar; David Kowbel; Pieter-Jaap Krijtenburg; Daniel Pinkel; Fritz H Schröder; Kees J Vissers; Vivienne J E Watson; Mark F Wildhagen; Colin Collins; Herman Van Dekken
Journal:  Am J Pathol       Date:  2003-03       Impact factor: 4.307

8.  High-level expression of cutaneous fatty acid-binding protein in prostatic carcinomas and its effect on tumorigenicity.

Authors:  Janet Adamson; Elwin A Morgan; Carol Beesley; Yongqiang Mei; Christopher S Foster; Hiroshi Fujii; Philip S Rudland; Paul H Smith; Youqiang Ke
Journal:  Oncogene       Date:  2003-05-08       Impact factor: 9.867

9.  Clinical significance of alterations of chromosome 8 detected by fluorescence in situ hybridization analysis in pathologic organ-confined prostate cancer.

Authors:  Norihiko Tsuchiya; Jeffrey M Slezak; Michael M Lieber; Erik J Bergstralh; Robert B Jenkins
Journal:  Genes Chromosomes Cancer       Date:  2002-08       Impact factor: 5.006

10.  Chromosomal changes during development and progression of prostate adenocarcinomas.

Authors:  H Zitzelsberger; D Engert; A Walch; U Kulka; M Aubele; H Höfler; M Bauchinger; M Werner
Journal:  Br J Cancer       Date:  2001-01       Impact factor: 7.640

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  14 in total

1.  Challenges in identifying candidate amplification targets in human cancers: chromosome 8q21 as a case study.

Authors:  Jennifer A Byrne; Yuyan Chen; Nancy Martin La Rotta; Gregory B Peters
Journal:  Genes Cancer       Date:  2012-02

2.  Biological resonance for cancer metastasis, a new hypothesis based on comparisons between primary cancers and metastases.

Authors:  Dongwei Gao; Sha Li
Journal:  Cancer Microenviron       Date:  2013-11-10

3.  ERG rearrangement metastasis patterns in locally advanced prostate cancer.

Authors:  Sven Perner; Maria A Svensson; Ruhella R Hossain; John R Day; Jack Groskopf; Ryan C Slaughter; Analee R Jarleborn; Matthias D Hofer; Rainer Kuefer; Francesca Demichelis; David S Rickman; Mark A Rubin
Journal:  Urology       Date:  2010-04       Impact factor: 2.649

4.  Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer.

Authors:  Wennuan Liu; Chunmei Carol Xie; Yi Zhu; Tao Li; Jishan Sun; Yu Cheng; Charles M Ewing; Sue Dalrymple; Aubrey R Turner; Jielin Sun; John T Isaacs; Bao-Li Chang; Siqun Lilly Zheng; William B Isaacs; Jianfeng Xu
Journal:  Neoplasia       Date:  2008-08       Impact factor: 5.715

5.  Neoplasia: the second decade.

Authors:  Alnawaz Rehemtulla
Journal:  Neoplasia       Date:  2008-12       Impact factor: 5.715

6.  High resolution oligonucleotide CGH using DNA from archived prostate tissue.

Authors:  Pamela L Paris; Shivaranjani Sridharan; Alicia Scheffer; Anya Tsalenko; Laurakay Bruhn; Colin Collins
Journal:  Prostate       Date:  2007-09-15       Impact factor: 4.104

7.  DNA copy number aberrations in breast cancer by array comparative genomic hybridization.

Authors:  Jian Li; Kai Wang; Shengting Li; Vera Timmermans-Wielenga; Fritz Rank; Carsten Wiuf; Xiuqing Zhang; Huanming Yang; Lars Bolund
Journal:  Genomics Proteomics Bioinformatics       Date:  2009-06       Impact factor: 7.691

8.  Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells.

Authors:  Euan S Polson; John L Lewis; Hamza Celik; Vincent M Mann; Michael J Stower; Matthew S Simms; Greta Rodrigues; Anne T Collins; Norman J Maitland
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

9.  Identification of ovarian cancer metastatic miRNAs.

Authors:  Souriya Vang; Hsin-Ta Wu; Andrew Fischer; Daniel H Miller; Shannon MacLaughlan; Elijah Douglass; Lauren Comisar; Margaret Steinhoff; Colin Collins; Peter J S Smith; Laurent Brard; Alexander S Brodsky
Journal:  PLoS One       Date:  2013-03-12       Impact factor: 3.240

10.  Expression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease.

Authors:  Alexander S Brodsky; Andrew Fischer; Daniel H Miller; Souriya Vang; Shannon MacLaughlan; Hsin-Ta Wu; Jovian Yu; Margaret Steinhoff; Colin Collins; Peter J S Smith; Benjamin J Raphael; Laurent Brard
Journal:  PLoS One       Date:  2014-04-14       Impact factor: 3.240

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