| Literature DB >> 17217304 |
Hideaki Watanabe1, Masashi Takano, Akinori Umino, Toshiya Ito, Hiroyuki Ishikawa, Masahisa Nakada.
Abstract
The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric catalysis developed by us and highly stereoselective construction of all stereogenic centers in the aglycon. [reaction: see text].Entities:
Mesh：
Substances：
Year: 2007 PMID： 17217304 DOI： 10.1021/ol0628816
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005