Literature DB >> 17217296

Total synthesis of bistramide A.

Jason T Lowe1, Iwona E Wrona, James S Panek.   

Abstract

An asymmetric synthesis of the marine metabolite bistramide A is reported. The synthesis relies on the utility of three different organosilane reagents to construct all principle fragments and 8 of the 11 stereogenic centers of the natural product. [structure: see text].

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Year:  2007        PMID： 17217296     DOI： 10.1021/ol062957y

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  8 in total

1.  Diastereoselective, three-component cascade synthesis of tetrahydrofurans and tetrahydropyrans employing the tandem Mukaiyama aldol-lactonization process.

Authors:  T Andrew Mitchell; Cunxiang Zhao; Daniel Romo
Journal:  J Org Chem       Date:  2008-12-19       Impact factor: 4.354

2.  INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS.

Authors:  Tadeusz F Molinski; Brandon I Morinaka
Journal:  Tetrahedron       Date:  2012-11-18       Impact factor: 2.457

3.  One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes.

Authors:  Vladimir A Maslivetc; Marina Rubina; Michael Rubin
Journal:  Org Biomol Chem       Date:  2015-08-05       Impact factor: 3.876

4.  Spiroacetal formation through telescoped cycloaddition and carbon-hydrogen bond functionalization: total synthesis of bistramide A.

Authors:  Xun Han; Paul E Floreancig
Journal:  Angew Chem Int Ed Engl       Date:  2014-09-04       Impact factor: 15.336

5.  Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth.

Authors:  Iwona E Wrona; Jason T Lowe; Thomas J Turbyville; Tanya R Johnson; Julien Beignet; John A Beutler; James S Panek
Journal:  J Org Chem       Date:  2009-03-06       Impact factor: 4.354

Review 6.  Asymmetric synthesis of naturally occurring spiroketals.

Authors:  B Rama Raju; Anil K Saikia
Journal:  Molecules       Date:  2008-08-28       Impact factor: 4.411

7.  A Domino 10-Step Total Synthesis of FR252921 and Its Analogues, Complex Macrocyclic Immunosuppressants.

Authors:  Yong Chen; Guilhem Coussanes; Caroline Souris; Paul Aillard; Dainis Kaldre; Kathrin Runggatscher; Stefan Kubicek; Giovanni Di Mauro; Boris Maryasin; Nuno Maulide
Journal:  J Am Chem Soc       Date:  2019-08-22       Impact factor: 16.383

Review 8.  Contemporary Strategies for the Synthesis of Tetrahydropyran Derivatives: Application to Total Synthesis of Neopeltolide, a Marine Macrolide Natural Product.

Authors:  Haruhiko Fuwa
Journal:  Mar Drugs       Date:  2016-03-25       Impact factor: 5.118
  8 in total

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