| Literature DB >> 17217287 |
Gang Xu1, Ai-Jun Hou, Yong-Tang Zheng, Yu Zhao, Xiao-Li Li, Li-Yan Peng, Qin-Shi Zhao.
Abstract
Przewalskin B (1), a novel diterpenoid possessing a unique skeleton, was isolated from a Chinese medicinal plant Salvia przewalskii. Its structure and relative stereochemistry were elucidated by extensive NMR analysis and a single-crystal X-ray study. A possible biosynthetic pathway for 1 was proposed. Compound 1 exhibited modest anti-HIV-1 activity with EC50 = 30 microg/mL. [structure: see text].Entities:
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Year: 2007 PMID： 17217287 DOI： 10.1021/ol062748d
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005