Literature DB >> 17217037

The PLZF gene of t (11;17)-associated APL.

M J McConnell1, J D Licht.   

Abstract

The PLZF gene is one of five partners fused to the retinoic acid receptor alpha in acute promyelocytic leukemia. PLZF encodes a DNA-binding transcriptional repressor and the PLZF-RARalpha fusion protein like other RARalpha fusions can inhibit the genetic program mediated by the wild tpe retinoic acid receptor. However an increasing body of literature indicates an important role for the PLZF gene in growth control and development. This information suggests that loss of PLZF function might also contribute to leukemogenesis.

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Year:  2007        PMID： 17217037     DOI： 10.1007/978-3-540-34594-7_3

Source DB:  PubMed          Journal:  Curr Top Microbiol Immunol        ISSN： 0070-217X            Impact factor:   4.291


  13 in total

1.  PLZF regulates CCR6 and is critical for the acquisition and maintenance of the Th17 phenotype in human cells.

Authors:  Satya P Singh; Hongwei H Zhang; Hsinyi Tsang; Paul J Gardina; Timothy G Myers; Vijayaraj Nagarajan; Chang Hoon Lee; Joshua M Farber
Journal:  J Immunol       Date:  2015-04-01       Impact factor: 5.422

2.  Understanding PLZF: two transcriptional targets, REDD1 and smooth muscle α-actin, define new questions in growth control, senescence, self-renewal and tumor suppression.

Authors:  Marina Kolesnichenko; Peter K Vogt
Journal:  Cell Cycle       Date:  2011-03-01       Impact factor: 4.534

3.  Plzf regulates germline progenitor self-renewal by opposing mTORC1.

Authors:  Robin M Hobbs; Marco Seandel; Ilaria Falciatori; Shahin Rafii; Pier Paolo Pandolfi
Journal:  Cell       Date:  2010-08-06       Impact factor: 41.582

4.  The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions.

Authors:  Damian Kovalovsky; Olisambu U Uche; Sonia Eladad; Robin M Hobbs; Woelsung Yi; Eric Alonzo; Kevin Chua; Maggie Eidson; Hye-Jung Kim; Jin S Im; Pier Paolo Pandolfi; Derek B Sant'Angelo
Journal:  Nat Immunol       Date:  2008-07-27       Impact factor: 25.606

5.  A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation.

Authors:  Dorothy F Sobieszczuk; Alexei Poliakov; Qiling Xu; David G Wilkinson
Journal:  Genes Dev       Date:  2010-01-15       Impact factor: 11.361

6.  PLZF/ZBTB16, a glucocorticoid response gene in acute lymphoblastic leukemia, interferes with glucocorticoid-induced apoptosis.

Authors:  Muhammad Wasim; Michela Carlet; Muhammad Mansha; Richard Greil; Christian Ploner; Alexander Trockenbacher; Johannes Rainer; Reinhard Kofler
Journal:  J Steroid Biochem Mol Biol       Date:  2010-05-06       Impact factor: 4.292

7.  Promyelocytic leukaemia zinc finger maintains self-renewal of male germline stem cells (mGSCs) and its expression pattern in dairy goat testis.

Authors:  W Song; H Zhu; M Li; N Li; J Wu; H Mu; X Yao; W Han; W Liu; J Hua
Journal:  Cell Prolif       Date:  2013-08       Impact factor: 6.831

8.  The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival.

Authors:  M Cheung; J Pei; Y Pei; S C Jhanwar; H I Pass; J R Testa
Journal:  Oncogene       Date:  2009-12-14       Impact factor: 9.867

9.  Zbtb16 has a role in brown adipocyte bioenergetics.

Authors:  C L Plaisier; B J Bennett; A He; B Guan; A J Lusis; K Reue; L Vergnes
Journal:  Nutr Diabetes       Date:  2012-09-17       Impact factor: 5.097

10.  BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.

Authors:  Rebecca Mathew; Michael P Seiler; Seth T Scanlon; Ai-ping Mao; Michael G Constantinides; Clara Bertozzi-Villa; Jeffrey D Singer; Albert Bendelac
Journal:  Nature       Date:  2012-10-21       Impact factor: 49.962
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