Literature DB >> 17216580

In vitro bioactivity of novel tricalcium silicate ceramics.

Wenyuan Zhao1, Jiang Chang, Junying Wang, Wanyin Zhai, Zheng Wang.   

Abstract

In this study, bone-like apatite-formation ability of tricalcium silicate (Ca(3)SiO(5)) ceramics in simulated body fluid (SBF) was evaluated and the in vitro degradability was investigated by soaking in Ringer's solution. The effect of ionic products from Ca(3)SiO(5) dissolution on osteobalsts proliferation was investigated. The result indicated that hydroxyapatite (HA) was formed on the surface of the Ca(3)SiO(5) ceramics after soaking in SBF for 1 day, and Ca(3)SiO(5) ceramics could degraded in Ringer's solution. The Si ions from Ca(3)SiO(5) dissolution at certain concentration range significantly stimulated osteoblasts proliferation. Our results show that Ca(3)SiO(5) ceramics possess bone-like apatite-formation ability and degradability, and can release soluble ionic products to stimulate cell proliferation.

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Year:  2007        PMID: 17216580     DOI: 10.1007/s10856-006-0069-y

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN: 0957-4530            Impact factor:   4.727


  13 in total

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5.  Osteoblast attachment and mineralized nodule formation on rough and smooth 45S5 bioactive glass monoliths.

Authors:  J E Gough; I Notingher; L L Hench
Journal:  J Biomed Mater Res A       Date:  2004-03-15       Impact factor: 4.396

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Journal:  Biomaterials       Date:  2001-07       Impact factor: 12.479

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  7 in total

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7.  An evaluation of the inflammatory response of lipopolysaccharide-treated primary dental pulp cells with regard to calcium silicate-based cements.

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Journal:  Int J Oral Sci       Date:  2014-02-21       Impact factor: 6.344

  7 in total

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