| Literature DB >> 1721648 |
Abstract
Various aspects of antigen degradation and presentation are reviewed, in particular with respect to fragmentation of native vs. denatured proteins, different enzymatic machinery present in different cells and individuals, characterization of epitopes and their persistence on antigen-presenting cells as well as their capacity to interact with different MHC class II molecules. Finally, the structure of antigenic peptides is discussed.Mesh:
Substances:
Year: 1991 PMID: 1721648 DOI: 10.3109/08830189109061771
Source DB: PubMed Journal: Int Rev Immunol ISSN: 0883-0185 Impact factor: 5.311