Literature DB >> 17216436

Management of potential drug interactions in community pharmacies: a questionnaire-based survey in Switzerland.

Jörg Indermitte1, Laura Erba, Marianne Beutler, Rudolf Bruppacher, Walter E Haefeli, Kurt E Hersberger.   

Abstract

OBJECTIVE: To analyze the current drug-interaction management in Swiss community pharmacies, with a particular focus on electronic systems, and to compare the results with those expressed by German general practitioners in a recent survey.
METHODS: Data were collected with a postal questionnaire which was randomly sent to 500 out of 833 community pharmacies in the German part of Switzerland.
RESULTS: The response rate was 57.4%, and only 24.7% pharmacists reported that they were confronted less than daily with potential drug interactions. Use of computer software to identify potential drug interactions was widespread in community pharmacies (90.2%), and the software was the primary source of information (81.2 +/- 29.6%). The quality of the interaction software was judged sensitive (identifying all dangerous interactions) by 80.5 +/- 21.5%, but specific (identifying only relevant interactions) by only 38.3 +/- 32%. Pharmacists declared a low override rate (14%) of drug interaction alerts, although unjustified alerts were reported by 60.6 +/- 33.1%. In contrast to general practitioners, pharmacists opted less often for information on the mechanism of the interaction, and more frequently for details for dose adjustment. Both groups complained about deficient information on non-interacting alternatives.
CONCLUSION: The information needs of community pharmacists differed considerably from general practitioners, and pharmacists were overwhelmed by inappropriate alerts because of a lack of specificity of their drug-interaction systems. Substantial improvement of drug-interaction software systems is thus required at least in two important aspects, the suppression of inappropriate alerts and the tailoring to the needs of the user.

Mesh:

Year:  2007        PMID: 17216436     DOI: 10.1007/s00228-006-0237-5

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


  29 in total

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Review 2.  The role of pharmacy computer systems in preventing medication errors.

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4.  Requirements for a successful implementation of drug interaction information systems in general practice: results of a questionnaire survey in Germany.

Authors:  Verena Bergk; Christiane Gasse; Rainer Schnell; Walter E Haefeli
Journal:  Eur J Clin Pharmacol       Date:  2004-09-04       Impact factor: 2.953

5.  Community pharmacists' responses to drug-drug interaction alerts.

Authors:  John E Murphy; Ryan A Forrey; Usha Desiraju
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6.  Electronic medical alerts--so simple, so complex.

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7.  Preventing drug interactions by online prescription screening in community pharmacies and medical practices.

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8.  Incidence and preventability of adverse drug events among older persons in the ambulatory setting.

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Review 9.  Epidemiology of drug-drug interactions as a cause of hospital admissions.

Authors:  C A Jankel; L K Fitterman
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Journal:  Pharm World Sci       Date:  1995-09-22
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  10 in total

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Journal:  Eur J Clin Pharmacol       Date:  2013-12-05       Impact factor: 2.953

2.  Prevalence of adverse drug combinations in a large post-mortem toxicology database.

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4.  Comparative performance of two drug interaction screening programmes analysing a cross-sectional prescription dataset of 84,625 psychiatric inpatients.

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5.  Interpretation of clinical guidelines for poisoned patients: positive and negative effects of standard phrases used in TOXBASE.

Authors:  W S Waring; S H McDonald; A M Good; L D Gordon; D N Bateman
Journal:  Eur J Clin Pharmacol       Date:  2009-06-11       Impact factor: 2.953

6.  Hospital Pharmacists' Perceptions and Decision-Making Related to Drug-Drug Interactions.

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7.  Hospital discharge: What are the problems, information needs and objectives of community pharmacists? A mixed method approach.

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Journal:  Pharm Pract (Granada)       Date:  2017-08-25

8.  The Practice of the Community Pharmacists in Managing Potential Drug-Drug Interactions: A Simulated Patient Visits.

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Journal:  Integr Pharm Res Pract       Date:  2022-03-15

9.  Co-prescription of metoprolol and CYP2D6-inhibiting antidepressants before and after implementation of an optimized drug interaction database in Norway.

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10.  Evaluation of drug information resources for drug-ethanol and drug-tobacco interactions.

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  10 in total

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