| Literature DB >> 17216314 |
N Van Hoof1, D Courtheyn, W Gillis, J Van Hende, C Van Peteghem, M Van de Wiele, S Poelmans, H Noppe, C Van Poucke, E Cobbaert, P Vanthemse, H F De Brabander.
Abstract
The use of anabolic steroids has been banned in the European Union since 1981. In this study, the metabolism of the anabolic steroid methenolone acetate, was investigated in a male veal calf. After daily oral administration of methenolone acetate, three main metabolites were detected in both urine and faeces samples. Among these metabolites, alpha-methenolone was apparently the main one, but 1-methyl-5alpha-androstan-3,17-diol and 3alpha-hydroxy-1-methyl-5alpha-androstan-17-one were also observed. The parent compound was still detectable in faeces. As a consequence, abuse of methenolone acetate as growth promoter can be monitored by analysing urine and faeces samples. A few days after the last treatment, however, no metabolites were observed. Alpha-methenolone was detectable in urine until 5 days after the last treatment, but in faeces no metabolites were detectable after 3 days.Entities:
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Year: 2006 PMID： 17216314 DOI： 10.1007/s11259-006-3432-z
Source DB: PubMed Journal: Vet Res Commun ISSN： 0165-7380 Impact factor: 2.459