Literature DB >> 17215745

Preventable deaths from hemorrhage at a level I Canadian trauma center.

Homer C Tien1, Fernando Spencer, Lorraine N Tremblay, Sandro B Rizoli, Frederick D Brenneman.   

Abstract

BACKGROUND: Studies of trauma deaths have had a tremendous impact on the quality of contemporary trauma care. We studied causes of trauma death at a Level I Canadian trauma center, and tabulated preventable deaths from hemorrhage using explicit criteria.
METHODS: Trauma registry data were used to identify all trauma deaths at our institution from January 1, 1999 to December 31, 2003. Demographics, mechanism, and time or location of death were recorded. Registry data analysis and selective chart or autopsy review were then performed to assign causes of death.
RESULTS: A total of 558 consecutive trauma deaths were reviewed. Mean age was 48.7 (46.7-50.6), and mean Injury Severity Score was 38.8 (37.6-40.0); 29% were females. Blunt trauma represented 87% of all cases; penetrating injuries were only 13%. Central nervous system (CNS) injuries were the most frequent cause of death (60%), followed by hemorrhage (15%), and then combination CNS and hemorrhagic injuries (11%). Multiple organ failure caused 5% of deaths and 9% of deaths were from other causes. Of hemorrhagic deaths, 48% (n = 41) were from blunt injury, and 52% (n = 45) were from a penetrating mechanism. Of these hemorrhagic deaths, 16% were judged to be preventable because of significant delays in identifying the major source of hemorrhage. Hemorrhage from blunt pelvic injury was the major cause of exsanguination in 12 of 14 of these preventable deaths.
CONCLUSIONS: Blunt injury is the major mechanism leading to trauma deaths. Massive bleeding from blunt pelvic injury is the major cause of preventable hemorrhagic deaths in our study.

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Year:  2007        PMID: 17215745     DOI: 10.1097/01.ta.0000251558.38388.47

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  74 in total

1.  Clotting factor deficiency in early trauma-associated coagulopathy.

Authors:  Sandro B Rizoli; Sandro Scarpelini; Jeannie Callum; Bartolomeu Nascimento; Kenneth G Mann; Ruxandra Pinto; Jan Jansen; Homer C Tien
Journal:  J Trauma       Date:  2011-11

2.  Cause and timing of death in massively transfused trauma patients.

Authors:  Michael W Cripps; Matthew E Kutcher; Aaron Daley; Ryan C McCreery; Molly D Greenberg; Leslie M Cachola; Brittney J Redick; Mary F Nelson; Mitchell Jay Cohen
Journal:  J Trauma Acute Care Surg       Date:  2013-08       Impact factor: 3.313

3.  Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study.

Authors:  Mohammad H Rahbar; Erin E Fox; Deborah J del Junco; Bryan A Cotton; Jeanette M Podbielski; Nena Matijevic; Mitchell J Cohen; Martin A Schreiber; Jiajie Zhang; Parsa Mirhaji; Sarah J Duran; Robert J Reynolds; Ruby Benjamin-Garner; John B Holcomb
Journal:  Resuscitation       Date:  2011-10-12       Impact factor: 5.262

4.  Multicenter retrospective study of noncompressible torso hemorrhage: Anatomic locations of bleeding and comparison of endovascular versus open approach.

Authors:  Ronald Chang; Erin E Fox; Thomas J Greene; Brian J Eastridge; Ramyar Gilani; Kevin K Chung; Stacia M DeSantis; Joseph J DuBose; Jeffrey S Tomasek; Gerald R Fortuna; Valerie G Sams; S Rob Todd; Jeanette M Podbielski; Charles E Wade; John B Holcomb
Journal:  J Trauma Acute Care Surg       Date:  2017-07       Impact factor: 3.313

5.  Analysis of Injury and Mortality Patterns in Deceased Patients with Road Traffic Injuries: An Autopsy Study.

Authors:  Roman Pfeifer; Sylvia Schick; Christopher Holzmann; Matthias Graw; Michel Teuben; Hans-Christoph Pape
Journal:  World J Surg       Date:  2017-12       Impact factor: 3.352

6.  Resuscitative endovascular balloon occlusion of the aorta: what is the optimum occlusion time in an ovine model of hemorrhagic shock?

Authors:  V A Reva; Y Matsumura; T Hörer; D A Sveklov; A V Denisov; S Y Telickiy; A B Seleznev; E R Bozhedomova; J Matsumoto; I M Samokhvalov; J J Morrison
Journal:  Eur J Trauma Emerg Surg       Date:  2016-10-13       Impact factor: 3.693

Review 7.  RBC Transfusion Strategies in the ICU: A Concise Review.

Authors:  Casey A Cable; Seyed Amirhossein Razavi; John D Roback; David J Murphy
Journal:  Crit Care Med       Date:  2019-11       Impact factor: 7.598

8.  The use of whole blood in traumatic bleeding: a systematic review.

Authors:  Mario Cruciani; Massimo Franchini; Carlo Mengoli; Giuseppe Marano; Ilaria Pati; Francesca Masiello; Eva Veropalumbo; Simonetta Pupella; Stefania Vaglio; Vanessa Agostini; Giancarlo Maria Liumbruno
Journal:  Intern Emerg Med       Date:  2020-09-15       Impact factor: 3.397

9.  Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: design, rationale and implementation.

Authors:  Sarah Baraniuk; Barbara C Tilley; Deborah J del Junco; Erin E Fox; Gerald van Belle; Charles E Wade; Jeanette M Podbielski; Angela M Beeler; John R Hess; Eileen M Bulger; Martin A Schreiber; Kenji Inaba; Timothy C Fabian; Jeffrey D Kerby; Mitchell Jay Cohen; Christopher N Miller; Sandro Rizoli; Thomas M Scalea; Terence O'Keeffe; Karen J Brasel; Bryan A Cotton; Peter Muskat; John B Holcomb
Journal:  Injury       Date:  2014-06-10       Impact factor: 2.586

Review 10.  The value of postmortem computed tomography as an alternative for autopsy in trauma victims: a systematic review.

Authors:  M Scholing; T P Saltzherr; P H P Fung Kon Jin; K J Ponsen; J B Reitsma; J S Lameris; J C Goslings
Journal:  Eur Radiol       Date:  2009-05-21       Impact factor: 5.315

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