Literature DB >> 17215099

Initial and long-term outcome after palliative surgical drainage of 269 patients with malignant biliary obstruction.

K F D Kuhlmann1, D van Poll, S M M de Castro, N T van Heek, O R C Busch, T M van Gulik, H Obertop, D J Gouma.   

Abstract

AIMS: This study aimed to analyse the current outcome after palliative surgical drainage of malignant biliary obstruction.
METHOD: From 1992 to 2003, perioperative parameters and the incidence and indications of readmissions were analysed in 269 patients who underwent a palliative biliary bypass for periampullary carcinoma.
RESULTS: Hospital mortality occurred in seven patients and median postoperative stay was 10 days. Anastomotic leakage occurred in three patients and intraabdominal haemorrhage in eight patients. Overall 75 patients experienced a complication. Nine patients underwent a relaparotomy during initial hospital admission. Overall, 142 patients were readmitted, 13 for indications related to the biliary bypass, 11 for surgery-related indications. Twenty-five patients were readmitted for radiochemotherapy, 112 for progressive disease and 23 for indications not related to the disease. Median survival was 7.5 months and the 3-year survival 3%. Survival was significantly lower in patients with metastases and in those who underwent elective bypass for gastric outlet obstruction.
CONCLUSION: Current hospital mortality after palliative biliary bypass as well as readmission rates for complications related to the biliary bypass or surgical procedure are low. Surgical biliary bypass is a safe and effective palliative treatment for patients with malignant biliary obstruction.

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Year:  2007        PMID: 17215099     DOI: 10.1016/j.ejso.2006.11.014

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  6 in total

1.  Single-stage intraoperative transhepatic biliary stenting in patients with unresectable hepatobiliary pancreatic tumors.

Authors:  Yoshimi Iwasaki; Keiichi Kubota; Junji Kita; Masato Katoh; Mitsugi Shimoda; Tokihiko Sawada; Yukihiro Iso
Journal:  Surg Endosc       Date:  2012-07-18       Impact factor: 4.584

2.  Is intraoperative confirmation of malignancy during pancreaticoduodenectomy mandatory?

Authors:  Giuseppe Garcea; Matthew S Metcalfe; David P Berry; Gavin S Robertson; David M Lloyd; Ashley R Dennison
Journal:  J Gastrointest Surg       Date:  2011-10-28       Impact factor: 3.452

Review 3.  A meta-analysis of randomized trials: immediate stent placement vs. surgical bypass in the palliative management of malignant biliary obstruction.

Authors:  Evan S Glazer; Mark C Hornbrook; Robert S Krouse
Journal:  J Pain Symptom Manage       Date:  2013-07-03       Impact factor: 3.612

Review 4.  Drainage and bypass procedures for palliation of malignant diseases of the upper gastrointestinal tract.

Authors:  M T Huggett; P Ghaneh; S P Pereira
Journal:  Clin Oncol (R Coll Radiol)       Date:  2010-11       Impact factor: 4.126

5.  Guidelines for palliative surgery of cholangiocarcinoma.

Authors:  H Witzigmann; H Lang; H Lauer
Journal:  HPB (Oxford)       Date:  2008       Impact factor: 3.647

6.  Double bypass for inoperable pancreatic malignancy at laparotomy: postoperative complications and long-term outcome.

Authors:  F Ausania; A E Vallance; D M Manas; J M Prentis; C P Snowden; S A White; R M Charnley; J J French; B C Jaques
Journal:  Ann R Coll Surg Engl       Date:  2012-11       Impact factor: 1.891

  6 in total

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