Literature DB >> 17213356

Mixed epithelial and stromal tumour of the kidney with luteinised ovarian stroma.

C Buritica1, M Serrano, A Zuluaga, M Arrabal, S Regauer, F F Nogales.   

Abstract

We report a case of a 9-cm mixed epithelial and stromal tumour of the kidney in an obese 70-year-old woman with diabetes. The ovarian-type stroma had a spindle cell component that was positive for progesterone receptors and had the hitherto unreported presence of abundant foci of luteinised stromal cells with characteristic immunohistochemical positivity to alpha-inhibin, calretinin, aromatase and gonadotropin-releasing hormone (GnRH) receptors. We conclude that the stromal component is identical to ovarian cortical stroma. We believe that ovarian-type stroma occurs in extragenital tumours as a result of an epithelial-stromal interaction in an environment of hormonal hyperstimulation.

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Mesh：

Year:  2007        PMID： 17213356      PMCID： PMC1860583          DOI： 10.1136/jcp.2005.031294

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  13 in total

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4.  Mixed epithelial and stromal tumor of the kidney.

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9.  Ovarian-like stroma in an invasive mucinous cystadenocarcinoma of the pancreas positive for inhibin. A hint concerning its possible histogenesis.

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