Literature DB >> 17213306

Nonpeptidic glucagon-like peptide 1 receptor agonists: a magic bullet for diabetes?

K G Murphy1, S R Bloom.   

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Year:  2007        PMID： 17213306      PMCID： PMC1783373          DOI： 10.1073/pnas.0610679104

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  11 in total

Review 1.  New sources of pancreatic beta-cells.

Authors:  Susan Bonner-Weir; Gordon C Weir
Journal:  Nat Biotechnol       Date:  2005-07       Impact factor: 54.908

2.  Design and synthesis of a series of non-peptide high-affinity human corticotropin-releasing factor1 receptor antagonists.

Authors:  C Chen; R Dagnino; E B De Souza; D E Grigoriadis; C Q Huang; K I Kim; Z Liu; T Moran; T R Webb; J P Whitten; Y F Xie; J R McCarthy
Journal:  J Med Chem       Date:  1996-10-25       Impact factor: 7.446

3.  Small-molecule agonists for the glucagon-like peptide 1 receptor.

Authors:  Lotte Bjerre Knudsen; Dan Kiel; Min Teng; Carsten Behrens; Dilip Bhumralkar; János T Kodra; Jens J Holst; Claus B Jeppesen; Michael D Johnson; Johannes Cornelis de Jong; Anker Steen Jorgensen; Tim Kercher; Jarek Kostrowicki; Peter Madsen; Preben H Olesen; Jacob S Petersen; Fritz Poulsen; Ulla G Sidelmann; Jeppe Sturis; Larry Truesdale; John May; Jesper Lau
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-09       Impact factor: 11.205

4.  A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice.

Authors:  Desu Chen; Jiayu Liao; Na Li; Caihong Zhou; Qing Liu; Guangxing Wang; Rui Zhang; Song Zhang; Lilin Lin; Kaixian Chen; Xin Xie; Fajun Nan; Andrew A Young; Ming-Wei Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-09       Impact factor: 11.205

5.  Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist.

Authors:  H Doods; G Hallermayer; D Wu; M Entzeroth; K Rudolf; W Engel; W Eberlein
Journal:  Br J Pharmacol       Date:  2000-02       Impact factor: 8.739

Review 6.  Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter.

Authors:  Philip J Larsen; Jens Juul Holst
Journal:  Regul Pept       Date:  2005-06-15

7.  Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes.

Authors:  John B Buse; Robert R Henry; Jenny Han; Dennis D Kim; Mark S Fineman; Alain D Baron
Journal:  Diabetes Care       Date:  2004-11       Impact factor: 19.112

8.  Identification of alkylidene hydrazides as glucagon receptor antagonists.

Authors:  A Ling; Y Hong; J Gonzalez; V Gregor; A Polinsky; A Kuki; S Shi; K Teston; D Murphy; J Porter; D Kiel; J Lakis; K Anderes; J May; L B Knudsen; J Lau
Journal:  J Med Chem       Date:  2001-09-13       Impact factor: 7.446

9.  Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes.

Authors:  Ralph A DeFronzo; Robert E Ratner; Jenny Han; Dennis D Kim; Mark S Fineman; Alain D Baron
Journal:  Diabetes Care       Date:  2005-05       Impact factor: 19.112

10.  Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea.

Authors:  David M Kendall; Matthew C Riddle; Julio Rosenstock; Dongliang Zhuang; Dennis D Kim; Mark S Fineman; Alain D Baron
Journal:  Diabetes Care       Date:  2005-05       Impact factor: 19.112
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  8 in total

1.  Site of action of a pentapeptide agonist at the glucagon-like peptide-1 receptor. Insight into a small molecule agonist-binding pocket.

Authors:  Maoqing Dong; Delia I Pinon; Laurence J Miller
Journal:  Bioorg Med Chem Lett       Date:  2011-10-25       Impact factor: 2.823

2.  Non-peptidic glucose-like peptide-1 receptor agonists: aftermath of a serendipitous discovery.

Authors:  Ming-wei Wang; Qing Liu; Cai-hong Zhou
Journal:  Acta Pharmacol Sin       Date:  2010-08-02       Impact factor: 6.150

3.  Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice.

Authors:  Min He; Haoran Su; Weiwei Gao; Stina M Johansson; Qing Liu; Xiaoyan Wu; Jiayu Liao; Andrew A Young; Tamas Bartfai; Ming-Wei Wang
Journal:  PLoS One       Date:  2010-12-03       Impact factor: 3.240

4.  Molecular modeling of the three-dimensional structure of GLP-1R and its interactions with several agonists.

Authors:  Fu Lin; Renxiao Wang
Journal:  J Mol Model       Date:  2008-10-22       Impact factor: 1.810

5.  Synthesis and biological evaluation of glucagon-like peptide-1 receptor agonists.

Authors:  Yu-Juan Zhang; Liu-Lan Shen; Hyae-Gyeong Cheon; Yong-Nan Xu; Jin-Hyun Jeong
Journal:  Arch Pharm Res       Date:  2013-11-01       Impact factor: 4.946

6.  Glucagon-like peptide-1 (GLP-1) analogs: recent advances, new possibilities, and therapeutic implications.

Authors:  Bikash Manandhar; Jung-Mo Ahn
Journal:  J Med Chem       Date:  2014-11-13       Impact factor: 7.446

7.  Roux-en-Y gastric bypass alters intestinal glucose transport in the obese Zucker rat.

Authors:  Qinghe Meng; Derek M Culnan; Tamer Ahmed; Mingjie Sun; Robert N Cooney
Journal:  Front Endocrinol (Lausanne)       Date:  2022-08-11       Impact factor: 6.055

8.  Controlled Release of Pyrimidine Compound Using Polymeric Coated ZIF-8 Metal-Organic Framework as Glucagon-Like Peptide-1 Receptor Agonist Carrier.

Authors:  Shaikha S AlNeyadi; Naheed Amir; Mohammad A Ghattas; Noor Atatreh; Shaikha S Alketbi; Ruba Al Ajeil; Abdu Adem
Journal:  Molecules       Date:  2020-09-20       Impact factor: 4.411
  8 in total

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