Literature DB >> 17212945

Optimisation of contribution of candidate parents to maximise genetic gain and restricting inbreeding using semidefinite programming.

Ricardo Pong-Wong1, John A Woolliams.   

Abstract

An approach for optimising genetic contributions of candidates to control inbreeding in the offspring generation using semidefinite programming (SDP) was proposed. Formulations were done for maximising genetic gain while restricting inbreeding to a preset value and for minimising inbreeding without regard of gain. Adaptations to account for candidates with fixed contributions were also shown. Using small but traceable numerical examples, the SDP method was compared with an alternative based upon Lagrangian multipliers (RSRO). The SDP method always found the optimum solution that maximises genetic gain at any level of restriction imposed on inbreeding, unlike RSRO which failed to do so in several situations. For these situations, the expected gains from the solution obtained with RSRO were between 1.5-9% lower than those expected from the optimum solution found with SDP with assigned contributions varying widely. In conclusion SDP is a reliable and flexible method for solving contribution problems.

Entities:  

Mesh:

Year:  2007        PMID: 17212945      PMCID: PMC2739432          DOI: 10.1186/1297-9686-39-1-3

Source DB:  PubMed          Journal:  Genet Sel Evol        ISSN: 0999-193X            Impact factor:   4.297


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  11 in total

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4.  The effect of genomic information on optimal contribution selection in livestock breeding programs.

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7.  Effects of pedigree errors on the efficiency of conservation decisions.

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8.  A fast Newton-Raphson based iterative algorithm for large scale optimal contribution selection.

Authors:  Binyam S Dagnachew; Theo H E Meuwissen
Journal:  Genet Sel Evol       Date:  2016-09-20       Impact factor: 4.297

9.  The use of genomic coancestry matrices in the optimisation of contributions to maintain genetic diversity at specific regions of the genome.

Authors:  Fernando Gómez-Romano; Beatriz Villanueva; Jesús Fernández; John A Woolliams; Ricardo Pong-Wong
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10.  Selective advantage of implementing optimal contributions selection and timescales for the convergence of long-term genetic contributions.

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Journal:  Genet Sel Evol       Date:  2018-05-10       Impact factor: 4.297

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