Literature DB >> 17211615

[Practicability of a surgical multilevel therapy in patients with obstructive sleep apnea].

E A Stripf1, M Kühnemund, O Selivanova, W J Mann.   

Abstract

BACKGROUND: Obstructive sleep apnea syndrome is a "systemic disease" of the upper airways and the upper digestive tract. The concept of multilevel surgery takes account of the fact that the location of the obstruction frequently cannot be identified precisely. PATIENTS AND METHODS: In this retrospective study over 4 years, data on 25 patients (median age 49.9 years) with moderate to severe OSAS treated with a surgical multilevel therapy were statistically evaluated. The treatment carried out consisted in reduction of the inferior turbinate, if necessary combined with septum plasty, and conventional uvulopalatopharyngoplasty (UPPP), combined with tonsillectomy and radiofrequency therapy of the base of the tongue if appropriate. Pre- and postoperative clinical and polysomnographical checks were performed.
RESULTS: The mean apnea-hypopnea index (AHI) was 39.2+/-19.7/h before surgery. Postoperatively a highly significant reduction of AHI to 16.5+/-9.9/h (p<0.0001) was seen. In 13 out of 25 patients (52%) the disease was cured (AHI<20 and 50% reduction). In 23 patients the AHI improved. In 15 patients AHI was reduced by more than 50%.
CONCLUSION: Multilevel surgery should be considered as an alternative for patients suffering from OSAS, especially in view of the poor long-term results in patients who receive CPAP therapy or are intolerant to CPAP.

Entities:  

Mesh:

Year:  2007        PMID: 17211615     DOI: 10.1007/s00106-006-1486-4

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  29 in total

1.  Palatopharyngoglossoplasty in the treatment of patients with obstructive sleep apnea syndrome.

Authors:  G Djupesland; H Schrader; T Lyberg; H Refsum; F Lilleås; O B Godtlibsen
Journal:  Acta Otolaryngol Suppl       Date:  1992

2.  Predictors of symptoms of anxiety and depression in obstructive sleep apnea.

Authors:  Frank N Kjelsberg; Espen A Ruud; Knut Stavem
Journal:  Sleep Med       Date:  2005-07       Impact factor: 3.492

3.  Outcomes of hyoid suspension for the treatment of obstructive sleep apnea.

Authors:  Mary Talley Bowden; Eric J Kezirian; David Utley; Richard L Goode
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2005-05

Review 4.  Upper airway surgery for obstructive sleep apnea.

Authors:  Aaron E Sher
Journal:  Sleep Med Rev       Date:  2002-06       Impact factor: 11.609

5.  Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares.

Authors:  C E Sullivan; F G Issa; M Berthon-Jones; L Eves
Journal:  Lancet       Date:  1981-04-18       Impact factor: 79.321

6.  [Multi-level surgery for obstructive sleep apnea. Preliminary objective results].

Authors:  T Verse; A Baisch; K Hörmann
Journal:  Laryngorhinootologie       Date:  2004-08       Impact factor: 1.057

Review 7.  The efficacy of surgical modifications of the upper airway in adults with obstructive sleep apnea syndrome.

Authors:  A E Sher; K B Schechtman; J F Piccirillo
Journal:  Sleep       Date:  1996-02       Impact factor: 5.849

8.  The occurrence of sleep-disordered breathing among middle-aged adults.

Authors:  T Young; M Palta; J Dempsey; J Skatrud; S Weber; S Badr
Journal:  N Engl J Med       Date:  1993-04-29       Impact factor: 91.245

Review 9.  Recent developments in the treatment of obstructive sleep apnea.

Authors:  Thomas Verse; Wolfgang Pirsig; Boris A Stuck; Karl Hörmann; Joachim T Maurer
Journal:  Am J Respir Med       Date:  2003

10.  Same-stage palatopharyngeal and hypopharyngeal surgery for severe obstructive sleep apnea.

Authors:  Hsueh-Yu Li; Pa-Chun Wang; Chung-Yao Hsu; Ning-Hung Chen; Li-Ang Lee; Tuan-Jen Fang
Journal:  Acta Otolaryngol       Date:  2004-09       Impact factor: 1.494

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