Literature DB >> 17211406

Risk assessment of meat and milk from cloned animals.

Xiangzhong Yang1, X Cindy Tian, Chikara Kubota, Ray Page, Jie Xu, Jose Cibelli, George Seidel.   

Abstract

Research on, and commercialization of, cloned cattle has been conducted for more than 20 years. Early techniques relied on the physical splitting of embryos or using embryo cells for nuclear transfer to generate cloned animals. Milk and meat from these animals entered into the human food market with no evidence of problems. With the advent of nuclear transfer, which enables the direct transference and preservation of high-value meat- and milk-producing genotypes to offspring, concerns have been raised about whether the products from somatic cell nuclear transfer-produced animals are safe for human consumption. Studies on the biochemical properties of food products from cloned and noncloned animals have thus far not detected any differences. All data to date indicate no significant differences in the measured parameters between animals created by nuclear transfer and normally bred animals. Public acceptance of cloned animal products depends upon forthcoming US Food and Drug Administration approval along with convincing safety data.

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Year:  2007        PMID: 17211406     DOI: 10.1038/nbt1276

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN: 1087-0156            Impact factor:   54.908


  5 in total

1.  Quantification of leukocyte genomic 5-methylcytosine levels reveals epigenetic plasticity in healthy adult cloned cattle.

Authors:  Béatrice de Montera; Dalia El Zeihery; Sigrid Müller; Hélène Jammes; Gottfried Brem; Horst-Dieter Reichenbach; Fabian Scheipl; Pascale Chavatte-Palmer; Valeri Zakhartchenko; Oliver J Schmitz; Eckhard Wolf; Jean-Paul Renard; Stefan Hiendleder
Journal:  Cell Reprogram       Date:  2010-04       Impact factor: 1.987

2.  Effects of Genetically Modified Milk Containing Human Beta-Defensin-3 on Gastrointestinal Health of Mice.

Authors:  Xin Chen; Yange Yang; Zhaopeng Shi; Ming-Qing Gao; Yong Zhang
Journal:  PLoS One       Date:  2016-07-20       Impact factor: 3.240

3.  Comprehensive assessment of milk composition in transgenic cloned cattle.

Authors:  Ran Zhang; Chengdong Guo; Shunchao Sui; Tian Yu; Jianwu Wang; Ning Li
Journal:  PLoS One       Date:  2012-11-21       Impact factor: 3.240

4.  Aberrant epigenetic changes and gene expression in cloned cattle dying around birth.

Authors:  Li Lin; Qiang Li; Lei Zhang; Dingsheng Zhao; Yunping Dai; Ning Li
Journal:  BMC Dev Biol       Date:  2008-02-11       Impact factor: 1.978

5.  Dolly at 25… is she '… still goin' strong?'

Authors:  Kevin D Sinclair
Journal:  Reproduction       Date:  2021-06-21       Impact factor: 3.906

  5 in total

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