| Literature DB >> 17210482 |
Abstract
Prenatally, the umbilicus is of paramount importance, providing the gateway between the mother and the fetus. As the fetus becomes increasingly autonomous at the end of the second month of fetal life, the connections (vitelline, urachal) diminish in significance and involute. Disturbances in this process can result in a wide variety of abnormalities, ranging from relatively minor defects identified at birth (umbilical granulation tissue) to life-threatening complications quiescent until late adulthood (urachal carcinoma). This section will review the 'state of the art' in evaluation and management of these umbilical and related abnormalities.Entities:
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Year: 2007 PMID: 17210482 DOI: 10.1053/j.sempedsurg.2006.10.006
Source DB: PubMed Journal: Semin Pediatr Surg ISSN: 1055-8586 Impact factor: 2.754