Literature DB >> 172099

The effects of iron deficiency on rat liver enzymes.

R Bailey-Wood, L M Blayney, J R Muir, A Jacobs.   

Abstract

The effect of iron deficiency on a number or iron containing enzymes in rat liver has been examined. In addition, 6-phosphogluconate dehydrogenase and glucose 6-phosphate dehydrogenase have been assayed. Of the mitochondrial electron transport reactions only succinate-cytochrome C reductase activity was decreased in iron deficient animals. Microsomal reductase enzymes associated with the NADPH-oxidase system were also markedly decreased although cytochrome P450 concentrations were unaffected. Both 6-phosphogluconate dehydrogenase and glucose 6-phosphate dehydrogenase were reduced in young iron deficient rats but the former had returned to control levels at the age of 14 weeks.

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Year:  1975        PMID: 172099      PMCID: PMC2072701     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  18 in total

1.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE.

Authors:  T OMURA; R SATO
Journal:  J Biol Chem       Date:  1964-07       Impact factor: 5.157

2.  The cytochrome c content of the heart, kidney, liver and skeletal muscle of iron-deficient rats.

Authors:  H A SALMON
Journal:  J Physiol       Date:  1962-10       Impact factor: 5.182

3.  Studies on the electron transport system. XXX. DPNH-cytochrome c reductase I.

Authors:  Y HATEFI; A G HAAVIK
Journal:  Biochim Biophys Acta       Date:  1961-09-02

4.  Iron enzymes in iron deficiency. V. Succinic dehydrogenase in rat liver, kidney and heart.

Authors:  E BEUTLER; R K BLAISDELL
Journal:  Blood       Date:  1960-01       Impact factor: 22.113

5.  Iron enzymes in iron deficiency. IV. Cytochrome oxidase in rat kidney and heart.

Authors:  E BEUTLER
Journal:  Acta Haematol       Date:  1959-06       Impact factor: 2.195

6.  Iron-containing enzymes in the buccal epithelium.

Authors:  A JACOBS
Journal:  Lancet       Date:  1961-12-16       Impact factor: 79.321

7.  Iron enzymes in iron deficiency. I. Cytochrome c.

Authors:  E BEUTLER
Journal:  Am J Med Sci       Date:  1957-11       Impact factor: 2.378

8.  Further studies on the properties and assay of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase of rat liver.

Authors:  G E GLOCK; P McLEAN
Journal:  Biochem J       Date:  1953-10       Impact factor: 3.857

9.  A microspectrophotometric method for the determination of cytochrome oxidase.

Authors:  S J COOPERSTEIN; A LAZAROW
Journal:  J Biol Chem       Date:  1951-04       Impact factor: 5.157

10.  METHOD FOR THE AUTOMATIC DETERMINATION OF SERUM IRON.

Authors:  D S YOUNG; J M HICKS
Journal:  J Clin Pathol       Date:  1965-01       Impact factor: 3.411

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  6 in total

1.  Conversion of 5-aminolaevulinate into haem by homogenates of human liver. Comparison with rat and chick-embryo liver homogenates.

Authors:  H L Bonkovsky; J F Healey; P R Sinclair; J F Sinclair
Journal:  Biochem J       Date:  1985-05-01       Impact factor: 3.857

2.  Lactic acidosis as a result of iron deficiency.

Authors:  C A Finch; P D Gollnick; M P Hlastala; L R Miller; E Dillmann; B Mackler
Journal:  J Clin Invest       Date:  1979-07       Impact factor: 14.808

Review 3.  Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis.

Authors:  Umbreen Ahmed; Patricia S Latham; Phillip S Oates
Journal:  World J Gastroenterol       Date:  2012-09-14       Impact factor: 5.742

4.  Interrelationship between iron deficiency and lead intoxication (Part 2).

Authors:  N S Hashmi; D N Kachru; S Khandelwal; S K Tandon
Journal:  Biol Trace Elem Res       Date:  1989-12       Impact factor: 3.738

Review 5.  Hepatic heme metabolism and its control.

Authors:  H L Bonkowsky; P R Sinclair; J F Sinclair
Journal:  Yale J Biol Med       Date:  1979 Jan-Feb

6.  Nutrient-toxicant interactions: susceptible populations.

Authors:  K R Mahaffey; J E Vanderveen
Journal:  Environ Health Perspect       Date:  1979-04       Impact factor: 9.031

  6 in total

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