OBJECTIVE: To assess predictors of latent tuberculosis infection (LTBI) completion by using structural equation modeling (SEM) among homeless adults, a group at great risk for LTBI and active tuberculosis (TB). LTBI therapy is effective in stemming the progression to active TB, yet treatment adherence among homeless persons is difficult to attain. DESIGN: By using SEM, the authors assessed predictors of LTBI completion among a sample of 494 homeless adults in Los Angeles, CA, who received either anurse case-managed program (NCM) or a usual care program. MAIN OUTCOME MEASURES: Latent variables were created with the baseline variables of site type, age, intervention status, dissatisfaction with health care, depression, TB risk assessment, alcohol use, heroin or cocaine use, and TB knowledge. Outcome variables included many of the same baseline variables as well as treatment completion. RESULTS: LTBI treatment completion (100% adherence) was significantly and positively associated with participation in NCM, older age, and less heroin or cocaine use. NCM also predicted greater TB knowledge, greater ease of treatment, and more satisfaction with treatment (NCM completion rate = 64%, control rate = 42%). CONCLUSION: The culturally competent NCM program, combined with active tracking and incentives, was successful in a difficult-to-treat and highly transient population.
RCT Entities:
OBJECTIVE: To assess predictors of latent tuberculosis infection (LTBI) completion by using structural equation modeling (SEM) among homeless adults, a group at great risk for LTBI and active tuberculosis (TB). LTBI therapy is effective in stemming the progression to active TB, yet treatment adherence among homeless persons is difficult to attain. DESIGN: By using SEM, the authors assessed predictors of LTBI completion among a sample of 494 homeless adults in Los Angeles, CA, who received either a nurse case-managed program (NCM) or a usual care program. MAIN OUTCOME MEASURES: Latent variables were created with the baseline variables of site type, age, intervention status, dissatisfaction with health care, depression, TB risk assessment, alcohol use, heroin or cocaine use, and TB knowledge. Outcome variables included many of the same baseline variables as well as treatment completion. RESULTS: LTBI treatment completion (100% adherence) was significantly and positively associated with participation in NCM, older age, and less heroin or cocaine use. NCM also predicted greater TB knowledge, greater ease of treatment, and more satisfaction with treatment (NCM completion rate = 64%, control rate = 42%). CONCLUSION: The culturally competent NCM program, combined with active tracking and incentives, was successful in a difficult-to-treat and highly transient population.
Authors: Adeline Nyamathi; Peggy Compton; Allan Cohen; Mary Marfisee; Steven Shoptaw; Barbara Greengold; Viviana de Castro; Mashid Reaves; Albert Hasson; Daniel George; Barbara Leake Journal: West J Nurs Res Date: 2009-01-07 Impact factor: 1.967
Authors: Adeline Nyamathi; Benissa E Salem; Sanghyuk S Shin; Adrianna A Jones; Dana R Garfin; Kartik Yadav; Alicia H Chang; Kathryn White; Donald Morisky Journal: Nurs Res Date: 2021 Nov-Dec 01 Impact factor: 2.381
Authors: Qin Liu; Katharine Abba; Marissa M Alejandria; David Sinclair; Vincent M Balanag; Mary Ann D Lansang Journal: Cochrane Database Syst Rev Date: 2014-11-18
Authors: Peter Hanlon; Lynsey Yeoman; Lauren Gibson; Regina Esiovwa; Andrea E Williamson; Frances S Mair; Richard Lowrie Journal: BMJ Open Date: 2018-04-07 Impact factor: 2.692
Authors: Elizabeth E Lutge; Charles Shey Wiysonge; Stephen E Knight; David Sinclair; Jimmy Volmink Journal: Cochrane Database Syst Rev Date: 2015-09-03