| Literature DB >> 1720940 |
L Kopper1, A Bankfalvi, R Mihalik, P Nagy, C Fulop, G Sarmay.
Abstract
An in vitro cell line (HT 58) has been established from a human (B) NHL xenograft. The lymphoma cells in culture retained their lymphoblastic appearance, DNA-content, IgM/lambda monoclonality and many immunophenotypic markers. The clonal chromosomal abnormalities involved the chromosomes 1, 2, 3 and 14. The cells expressed and produced chondroitin sulfate proteoglycans identified with mAbs that were raised against human articular cartilage CSPG. The cells also released IgM into the medium as well as substances that stimulated the proliferation of activated normal peripheral B-cells.Entities:
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Year: 1991 PMID： 1720940
Source DB: PubMed Journal: Anticancer Res ISSN： 0250-7005 Impact factor: 2.480