| Literature DB >> 17207923 |
Alejandra Gorostizaga1, Fabiana Cornejo Maciel, Laura Brion, Paula Maloberti, Ernesto J Podestá, Cristina Paz.
Abstract
In adrenocortical and Leydig cells PKA activation by trophic hormones increases the activity of protein tyrosine phosphatases and also induces the expression of MAP kinase phosphatase 1 (MKP-1), a dual activity protein phosphatase (serine/threonine and tyrosine). This work summarizes the knowledge on the regulation and the role played by cAMP-activated tyrosine phosphatases as well as MKP-1 in the hormonal activation of the acute and chronic phases of steroidogenesis.Entities:
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Year: 2007 PMID： 17207923 DOI： 10.1016/j.mce.2006.12.009
Source DB: PubMed Journal: Mol Cell Endocrinol ISSN： 0303-7207 Impact factor: 4.102