Literature DB >> 17206734

Combined mass spectrometry and dynamic chemistry approach to identify metalloenzyme inhibitors.

Benoît M R Liénard1, Nathalie Selevsek, Neil J Oldham, Christopher J Schofield.   

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Year:  2007        PMID: 17206734     DOI: 10.1002/cmdc.200600250

Source DB:  PubMed          Journal:  ChemMedChem        ISSN: 1860-7179            Impact factor:   3.466


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  5 in total

1.  Synthesis, characterization, mechanism of decomposition, and antiproliferative activity of a class of PEGylated benzopolysulfanes structurally similar to the natural product varacin.

Authors:  Adaickapillai Mahendran; Angela Vuong; David Aebisher; Yaqiong Gong; Robert Bittman; Gilbert Arthur; Akira Kawamura; Alexander Greer
Journal:  J Org Chem       Date:  2010-08-20       Impact factor: 4.354

2.  Synthesis and antiproliferative properties of a new ceramide analog of varacin.

Authors:  Adaickapillai Mahendran; Ashwini A Ghogare; Robert Bittman; Gilbert Arthur; Alexander Greer
Journal:  Chem Phys Lipids       Date:  2015-08-05       Impact factor: 3.329

3.  Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism.

Authors:  Kristina M Cook; Stephen T Hilton; Jasmin Mecinovic; William B Motherwell; William D Figg; Christopher J Schofield
Journal:  J Biol Chem       Date:  2009-07-09       Impact factor: 5.157

Review 4.  Protein-Directed Dynamic Combinatorial Chemistry: A Guide to Protein Ligand and Inhibitor Discovery.

Authors:  Renjie Huang; Ivanhoe K H Leung
Journal:  Molecules       Date:  2016-07-16       Impact factor: 4.411

5.  Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.

Authors:  Nathan R Rose; Esther C Y Woon; Guy L Kingham; Oliver N F King; Jasmin Mecinović; Ian J Clifton; Stanley S Ng; Jobina Talib-Hardy; Udo Oppermann; Michael A McDonough; Christopher J Schofield
Journal:  J Med Chem       Date:  2010-02-25       Impact factor: 7.446

  5 in total

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