PURPOSE: To assess the reliability of sonography in differentiating benign from malignant thyroid nodules and selecting lesions for fine-needle aspiration (FNA). METHODS: During a 2-year period, the following 7 sonographic parameters were assessed in 129 patients with thyroid nodules: size, number, echogenicity, echotexure, margin regularity, presence of calcifications, and presence of a hypoechoic rim. Sonographically guided FNA was performed on thyroid nodules 5 mm in diameter. Out of 184 FNAs, we obtained 168 specimens adequate for cytologic analysis and 16 (9%) nondiagnostic specimens. RESULTS: FNA diagnoses included 150 (89%) benign and 18 (11%) malignant nodules. Among 53 solitary nodules, 11 were carcinomas and 42 were benign (p < 0.01). The mean size of the carcinomas was 28 +/- 12 mm versus 18 +/- 10 mm for benign nodules (p < 0.01). The following sonographic features were significantly associated with malignancy: hypoechogenicity, irregular margins, calcifications, and absence of a hypoechoic rim. Differences in echotexure between malignant and benign nodules were not statistically significant. CONCLUSION: Sonographically guided FNA should be performed on thyroid nodules 5 mm in diameter with sonographic characteristics that suggest malignancy. (c) 2006 Wiley Periodicals, Inc.
PURPOSE: To assess the reliability of sonography in differentiating benign from malignant thyroid nodules and selecting lesions for fine-needle aspiration (FNA). METHODS: During a 2-year period, the following 7 sonographic parameters were assessed in 129 patients with thyroid nodules: size, number, echogenicity, echotexure, margin regularity, presence of calcifications, and presence of a hypoechoic rim. Sonographically guided FNA was performed on thyroid nodules 5 mm in diameter. Out of 184 FNAs, we obtained 168 specimens adequate for cytologic analysis and 16 (9%) nondiagnostic specimens. RESULTS: FNA diagnoses included 150 (89%) benign and 18 (11%) malignant nodules. Among 53 solitary nodules, 11 were carcinomas and 42 were benign (p < 0.01). The mean size of the carcinomas was 28 +/- 12 mm versus 18 +/- 10 mm for benign nodules (p < 0.01). The following sonographic features were significantly associated with malignancy: hypoechogenicity, irregular margins, calcifications, and absence of a hypoechoic rim. Differences in echotexure between malignant and benign nodules were not statistically significant. CONCLUSION: Sonographically guided FNA should be performed on thyroid nodules 5 mm in diameter with sonographic characteristics that suggest malignancy. (c) 2006 Wiley Periodicals, Inc.
Authors: Seo Ki Kim; Jun Ho Lee; Jung-Woo Woo; Inhye Park; Jun-Ho Choe; Jung-Han Kim; Jee Soo Kim Journal: Medicine (Baltimore) Date: 2015-05 Impact factor: 1.889
Authors: Krzysztof Kaliszewski; Dorota Diakowska; Beata Wojtczak; Marta Strutyńska-Karpińska; Paweł Domosławski; Krzysztof Sutkowski; Mateusz Głód; Waldemar Balcerzak; Zdzisław Forkasiewicz; Tadeusz Łukieńczuk Journal: PLoS One Date: 2016-01-19 Impact factor: 3.240
Authors: Ibrahim Abobaker Al-Ghanimi; Abdulaziz Mohammad Al-Sharydah; Saqar Al-Mulhim; Sarah Faisal; Abdulrahman Al-Abdulwahab; Mohammed Al-Aftan; Abdulrahman Abuhaimed Journal: Saudi J Med Med Sci Date: 2019-12-23