| Literature DB >> 17204352 |
Massimiliano Ruscica1, Elena Dozio, Marcella Motta, Paolo Magni.
Abstract
The neuropeptide Y (NPY) family of peptides, in addition to its many physiological actions, has also been involved in the modulation of tumor progression, with specific reference to endocrine-related cancers such as neuroendocrine tumors, breast and prostate cancers. These have been found either to express NPY receptors, or to secrete NPY-related peptides, or both. The study of the role of the NPY family of peptides in the biology of endocrine-related tumors, specifically concerning cell proliferation, angiogenesis, invasion and metastatization, may help to clarify some aspects of tumor pathophysiology, as well as to indicate novel diagnostic markers and therapeutical approaches.Entities:
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Year: 2007 PMID： 17204352 DOI： 10.1016/j.peptides.2006.08.045
Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750