Literature DB >> 17204091

Expression of SpanX mRNA in testicular germ cell tumors.

Michele Salemi1, Aldo E Calogero, Paolo Bosco, Roberto Castiglione, Sandro La Vignera, Eugenia Borgione, Giancarlo Rappazzo, Enzo Vicari.   

Abstract

The function of SpanX proteins is unknown, evidence is accumulating to suggest their involvement in tumorigenesis. A locus in Xq27, where the SpanX gene family is located, has been associated with testicular germ cell tumor (TGCT) onset. Therefore, we evaluated the presence of SpanX mRNA in six TGCT cases by RT-PCR. The results showed that SpanX mRNA is present in TGCT, confirming transcriptional activity of these genes in such tumors.

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Year:  2006        PMID： 17204091     DOI： 10.1111/j.1749-0774.2006.00014.x

Source DB:  PubMed          Journal:  Hum Cell        ISSN： 0914-7470            Impact factor:   4.174


  14 in total

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Journal:  Science       Date:  2002-08-09       Impact factor: 47.728

2.  The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines.

Authors:  Albert J W Zendman; Jürgen Zschocke; Annemieke A van Kraats; Nicole J W de Wit; Maciej Kurpisz; Ulrich H Weidle; Dirk J Ruiter; Elisabeth H Weiss; Goos N P van Muijen
Journal:  Gene       Date:  2003-05-08       Impact factor: 3.688

3.  CTp11, a novel member of the family of human cancer/testis antigens.

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4.  Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27.

Authors:  Natalay Kouprina; Adam Pavlicek; Vladimir N Noskov; Greg Solomon; John Otstot; William Isaacs; John D Carpten; Jeffrey M Trent; Joanna Schleutker; J Carl Barrett; Jerzy Jurka; Vladimir Larionov
Journal:  Genome Res       Date:  2005-11       Impact factor: 9.043

5.  Spermatid-specific expression of the novel X-linked gene product SPAN-X localized to the nucleus of human spermatozoa.

Authors:  V A Westbrook; A B Diekman; K L Klotz; V V Khole; C von Kap-Herr; W L Golden; R L Eddy; T B Shows; M H Stoler; C Y Lee; C J Flickinger; J C Herr
Journal:  Biol Reprod       Date:  2000-08       Impact factor: 4.285

6.  The differential diagnosis of testicular germ cell tumors in theory and practice. A critical analysis of two major systems of classifiction and review of 389 cases.

Authors:  A R von Hochstetter; C E Hedinger
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1982-08

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Authors:  V Anne Westbrook; Pamela D Schoppee; Alan B Diekman; Kenneth L Klotz; Margaretta Allietta; Kevin T Hogan; Craig L Slingluff; James W Patterson; Henry F Frierson; William P Irvin; Charles J Flickinger; Michael A Coppola; John C Herr
Journal:  Clin Cancer Res       Date:  2004-01-01       Impact factor: 12.531

8.  Expression of SPANX proteins in human-ejaculated spermatozoa and sperm precursors.

Authors:  Michele Salemi; Aldo E Calogero; Daniela Di Benedetto; Anna Cosentino; Nunziata Barone; Giancarlo Rappazzo; Enzo Vicari
Journal:  Int J Androl       Date:  2004-06

9.  Localisation of susceptibility genes for familial testicular germ cell tumour.

Authors:  Elizabeth A Rapley; Gillian P Crockford; Douglas F Easton; Michael R Stratton; D Timothy Bishop
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10.  Risk of cancer in relatives of testicular cancer patients.

Authors:  K Heimdal; H Olsson; S Tretli; P Flodgren; A L Børresen; S D Fossa
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  7 in total

1.  SPANX-B and SPANX-C (Xq27 region) gene dosage analysis in Down's syndrome subjects with undescended testes.

Authors:  Michele Salemi; Corrado Romano; Concetta Barone; Francesco Calí; Filippo Caraci; Carmelo Romano; Cataldo Scavuzzo; Francesco Scillato; Maria Grazia Salluzzo; Maria Piccione; Manuela Martines; Giovanni Corsello; Ferdinando Nicoletti; Paolo Bosco
Journal:  J Genet       Date:  2009-04       Impact factor: 1.166

2.  Over expression of LDOC1 and PARP1, two pro-apoptotic genes, in a patient with cryptorchidism and DiGeorge anomaly.

Authors:  Michele Salemi; Roberto Castiglione; Sandro La Vignera; Rosita A Condorelli; Paolo Bosco; Enzo Vicari; Aldo E Calogero
Journal:  Hum Cell       Date:  2011-03-04       Impact factor: 4.174

3.  PARP1 and CASP3 gene expression in a patient with multiple head and neck squamous cell carcinoma and Parkinson disease.

Authors:  Aldo E Calogero; Pier Franco Soma; Maria C Giuffrida; Domenica Giuffrida; Sandro La Vignera; Carmelo Romano; Roberto Castiglione; Paolo Bosco; Michele Salemi
Journal:  Hum Cell       Date:  2011-06-05       Impact factor: 4.174

4.  Expression of STRBP mRNA in patients with cryptorchidism and Down's syndrome.

Authors:  M Salemi; S La Vignera; R Castiglione; R A Condorelli; L Cimino; P Bosco; C Romano; C Romano; A E Calogero
Journal:  J Endocrinol Invest       Date:  2012-01       Impact factor: 4.256

5.  Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4+ and CD8+ T cells.

Authors:  Giovanni Almanzar; Purevdorj B Olkhanud; Monica Bodogai; Chiara Dell'agnola; Dolgor Baatar; Stephen M Hewitt; Claudio Ghimenton; Mohan K Tummala; Ashani T Weeraratna; Keith Sean Hoek; Natalay Kouprina; Vladimir Larionov; Arya Biragyn
Journal:  Clin Cancer Res       Date:  2009-03-10       Impact factor: 12.531

6.  Expression of SPANX proteins in normal prostatic tissue and in prostate cancer.

Authors:  M Salemi; A E Calogero; G Zaccarello; R Castiglione; A Cosentino; C Campagna; E Vicari; G Rappazzo
Journal:  Eur J Histochem       Date:  2010       Impact factor: 3.188

7.  Evolutionary diversification of SPANX-N sperm protein gene structure and expression.

Authors:  Natalay Kouprina; Vladimir N Noskov; Adam Pavlicek; N Keith Collins; Pamela D Schoppee Bortz; Chris Ottolenghi; Dmitri Loukinov; Paul Goldsmith; John I Risinger; Jung-Hyun Kim; V Anne Westbrook; Gregory Solomon; Hanna Sounders; John C Herr; Jerzy Jurka; Victor Lobanenkov; David Schlessinger; Vladimir Larionov
Journal:  PLoS One       Date:  2007-04-04       Impact factor: 3.240
  7 in total

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