Literature DB >> 17203734

Hepatitis C, illicit drug use and public health: does Canada really have a viable plan?

Benedikt Fischer1, Kate Kalousek, Jürgen Rehm, Jeff Powis, Mel Krajden, Jens Reimer.   

Abstract

Some 300,000 individuals are infected with the hepatitis C virus (HCV) in Canada. HCV infection is associated with major morbidity, mortality and health care costs; these indicators are projected to rise over the next decade. The vast majority of prevalent and incident HCV infections in Canada are illicit drug use-related; thus, the HCV disease burden can only be addressed through interventions targeting this primary risk factor. Both preventive (e.g., needle exchange, methadone treatment) and therapeutic (e.g., the accessibility of HCV treatment for illicit drug users) interventions aimed at HCV in illicit drug users have been broadly expanded in Canada in recent years. However, evidence suggests that existing preventive measures only offer limited effectiveness in reducing HCV risk exposure. Also, due to restricted resources, treatment for HCV currently only reaches an extremely small proportion (i.e., <5%) of HCV-infected drug users. Thus, on the basis of current HCV incidence as well as given interventions and their impact, Canada is not achieving a net reduction in the prevalence of HCV-related to illicit drug use. In order to reduce the HCV disease burden, Canada needs to reconsider the scope, delivery and resourcing of both preventive and treatment interventions targeting the primary risk population of illicit drug users.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 17203734      PMCID: PMC6975722     

Source DB:  PubMed          Journal:  Can J Public Health        ISSN: 0008-4263


  35 in total

1.  Injection drug use and preventive measures: a comparison of Canadian and western European jurisdictions over time.

Authors:  B Fischer; J Rehm; T Blitz-Miller
Journal:  CMAJ       Date:  2000-06-13       Impact factor: 8.262

2.  Therapy for acute hepatitis C.

Authors:  J H Hoofnagle
Journal:  N Engl J Med       Date:  2001-11-15       Impact factor: 91.245

Review 3.  Safer injection facilities (SIFs) for injection drug users (IDUs) in Canada. A review and call for an evidence-focused pilot trial.

Authors:  Benedikt Fischer; Jürgen Rehm; Gregory Kim; Amanda Robins
Journal:  Can J Public Health       Date:  2002 Sep-Oct

Review 4.  Combating opiate dependence: a comparison among the available pharmacological options.

Authors:  Gerardo Gonzalez; Alison Oliveto; Thomas R Kosten
Journal:  Expert Opin Pharmacother       Date:  2004-04       Impact factor: 3.889

5.  Factors associated with interest in initiating treatment for hepatitis C Virus (HCV) infection among young HCV-infected injection drug users.

Authors:  Steffanie A Strathdee; M Latka; J Campbell; P T O'Driscoll; E T Golub; F Kapadia; R A Pollini; R S Garfein; D L Thomas; H Hagan
Journal:  Clin Infect Dis       Date:  2005-04-15       Impact factor: 9.079

Review 6.  Overcoming barriers to prevention, care, and treatment of hepatitis C in illicit drug users.

Authors:  Brian R Edlin; Thomas F Kresina; Daniel B Raymond; Michael R Carden; Marc N Gourevitch; Josiah D Rich; Laura W Cheever; Victoria A Cargill
Journal:  Clin Infect Dis       Date:  2005-04-15       Impact factor: 9.079

Review 7.  Epidemiology and natural history of hepatitis C virus infection in injection drug users: implications for treatment.

Authors:  Mark S Sulkowski; David L Thomas
Journal:  Clin Infect Dis       Date:  2005-04-15       Impact factor: 9.079

8.  Follow-up studies of treatment for hepatitis C virus infection among injection drug users.

Authors:  Olav Dalgard
Journal:  Clin Infect Dis       Date:  2005-04-15       Impact factor: 9.079

9.  Sharing of noninjection drug-use implements as a risk factor for hepatitis C.

Authors:  Stephanie Tortu; James M McMahon; Enrique R Pouget; Rahul Hamid
Journal:  Subst Use Misuse       Date:  2004-01       Impact factor: 2.164

10.  Infrequent reinfection after successful treatment for hepatitis C virus infection in injection drug users.

Authors:  Markus Backmund; Kirsten Meyer; Brian R Edlin
Journal:  Clin Infect Dis       Date:  2004-10-26       Impact factor: 9.079

View more
  2 in total

1.  A pilot training program for a motivational enhancement approach to hepatitis C virus treatment among individuals in Israeli methadone treatment centers.

Authors:  Diane S Morse; Miriam Schiff; Shabtay Levit; Rinat Cohen-Moreno; Geoffrey C Williams; Yehuda Neumark
Journal:  Subst Use Misuse       Date:  2012-01       Impact factor: 2.164

2.  Treatment of chronic hepatitis C infection among current and former injection drug users within a multidisciplinary treatment model at a community health centre.

Authors:  Adam Isaiah Newman; Shelley Beckstead; David Beking; Susan Finch; Tina Knorr; Carol Lynch; Meredith MacKenzie; Daphne Mayer; Brenda Melles; Ron Shore
Journal:  Can J Gastroenterol       Date:  2013-04       Impact factor: 3.522

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.