Literature DB >> 17203498

IAPP mimic blocks Abeta cytotoxic self-assembly: cross-suppression of amyloid toxicity of Abeta and IAPP suggests a molecular link between Alzheimer's disease and type II diabetes.

Li-Mei Yan1, Aleksandra Velkova, Marianna Tatarek-Nossol, Erika Andreetto, Aphrodite Kapurniotu.   

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Year:  2007        PMID： 17203498     DOI： 10.1002/anie.200604056

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  46 in total

1.  Polymorphic triple beta-sheet structures contribute to amide hydrogen/deuterium (H/D) exchange protection in the Alzheimer amyloid beta42 peptide.

Authors:  Buyong Ma; Ruth Nussinov
Journal:  J Biol Chem       Date:  2011-08-05       Impact factor: 5.157

2.  Combination of kinetically selected inhibitors in trans leads to highly effective inhibition of amyloid formation.

Authors:  Fanling Meng; Daniel P Raleigh; Andisheh Abedini
Journal:  J Am Chem Soc       Date:  2010-10-20       Impact factor: 15.419

3.  Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins.

Authors:  Sharmistha Sinha; Dahabada H J Lopes; Zhenming Du; Eric S Pang; Akila Shanmugam; Aleksey Lomakin; Peter Talbiersky; Annette Tennstaedt; Kirsten McDaniel; Reena Bakshi; Pei-Yi Kuo; Michael Ehrmann; George B Benedek; Joseph A Loo; Frank-Gerrit Klärner; Thomas Schrader; Chunyu Wang; Gal Bitan
Journal:  J Am Chem Soc       Date:  2011-09-29       Impact factor: 15.419

Review 4.  Amylin and its G-protein-coupled receptor: A probable pathological process and drug target for Alzheimer's disease.

Authors:  Wei Qiao Qiu
Journal:  Neuroscience       Date:  2017-05-19       Impact factor: 3.590

5.  Oligomerization of FVFLM peptides and their ability to inhibit beta amyloid peptides aggregation: consideration as a possible model.

Authors:  M Kouza; A Banerji; A Kolinski; I A Buhimschi; A Kloczkowski
Journal:  Phys Chem Chem Phys       Date:  2017-01-25       Impact factor: 3.676

6.  Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes.

Authors:  Idira Obasse; Mark Taylor; Nigel J Fullwood; David Allsop
Journal:  Interface Focus       Date:  2017-10-20       Impact factor: 3.906

Review 7.  Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis.

Authors:  Jinghui Luo; Sebastian K T S Wärmländer; Astrid Gräslund; Jan Pieter Abrahams
Journal:  J Biol Chem       Date:  2016-06-20       Impact factor: 5.157

Review 8.  Amyloid beta-protein assembly as a therapeutic target of Alzheimer's disease.

Authors:  Ghiam Yamin; Kenjiro Ono; Mohammed Inayathullah; David B Teplow
Journal:  Curr Pharm Des       Date:  2008       Impact factor: 3.116

9.  S100A6 amyloid fibril formation is calcium-modulated and enhances superoxide dismutase-1 (SOD1) aggregation.

Authors:  Hugo M Botelho; Sónia S Leal; Isabel Cardoso; Kiran Yanamandra; Ludmilla A Morozova-Roche; Günter Fritz; Cláudio M Gomes
Journal:  J Biol Chem       Date:  2012-10-17       Impact factor: 5.157

10.  Islet Amyloid Polypeptide Promotes Amyloid-Beta Aggregation by Binding-Induced Helix-Unfolding of the Amyloidogenic Core.

Authors:  Xinwei Ge; Ye Yang; Yunxiang Sun; Weiguo Cao; Feng Ding
Journal:  ACS Chem Neurosci       Date:  2018-02-09       Impact factor: 4.418
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