Literature DB >> 17202711

Bioactive constituents from Chinese natural medicines. XX. Inhibitors of antigen-induced degranulation in RBL-2H3 cells from the seeds of Psoralea corylifolia.

Hisashi Matsuda1, Sachiko Sugimoto, Toshio Morikawa, Koudai Matsuhira, Eri Mizuguchi, Seikou Nakamura, Masayuki Yoshikawa.   

Abstract

The ethyl acetate-soluble fraction of the methanolic extract from the seeds of Psoralea corylifolia was found to inhibit the release of beta-hexosaminidase, as a marker of antigen-IgE-induced degranulation in RBL-2H3 cells. Sixteen constituents were isolated from the ethyl acetate-soluble fraction and several constituents, Delta(1),3-hydroxybakuchiol (IC(50) = 49 microM), Delta(3),2-hydroxybakuchiol (69 microM, bavachin (58 microM), and psoralidin (ca. 100 microM), showed inhibitory activities against the antigen-induced degranulation.

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Year:  2007        PMID： 17202711     DOI： 10.1248/cpb.55.106

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  8 in total

1.  Degranulation inhibitors from the arils of Myristica fragrans in antigen-stimulated rat basophilic leukemia cells.

Authors:  Toshio Morikawa; Ikuko Hachiman; Kiyofumi Ninomiya; Hiroki Hata; Kaoru Sugawara; Osamu Muraoka; Hisashi Matsuda
Journal:  J Nat Med       Date:  2018-01-15       Impact factor: 2.343

2.  Total synthesis of psoralidin, an anticancer natural product.

Authors:  Pallab Pahari; Jürgen Rohr
Journal:  J Org Chem       Date:  2009-04-03       Impact factor: 4.354

3.  Psoralea corylifolia Linn.-"Kushtanashini".

Authors:  P S Khushboo; V M Jadhav; V J Kadam; N S Sathe
Journal:  Pharmacogn Rev       Date:  2010-01

Review 4.  Genus Psoralea: A review of the traditional and modern uses, phytochemistry and pharmacology.

Authors:  Bhupendra Koul; Pooja Taak; Arvind Kumar; Anil Kumar; Indraneel Sanyal
Journal:  J Ethnopharmacol       Date:  2018-12-03       Impact factor: 4.360

5.  Glucose Tolerance-Improving Activity of Helichrysoside in Mice and Its Structural Requirements for Promoting Glucose and Lipid Metabolism.

Authors:  Toshio Morikawa; Akifumi Nagatomo; Takahiro Oka; Yoshinobu Miki; Norihisa Taira; Megumi Shibano-Kitahara; Yuichiro Hori; Osamu Muraoka; Kiyofumi Ninomiya
Journal:  Int J Mol Sci       Date:  2019-12-14       Impact factor: 5.923

6.  Insecticidal and genotoxic activity of Psoralea corylifolia Linn. (Fabaceae) against Culex quinquefasciatus Say, 1823.

Authors:  Virendra K Dua; Arvind Kumar; Akhilesh C Pandey; Sandeep Kumar
Journal:  Parasit Vectors       Date:  2013-02-04       Impact factor: 3.876

7.  Diverse role of fast growing rhizobia in growth promotion and enhancement of psoralen content in Psoralea corylifolia L.

Authors:  Chandra Prabha; D K Maheshwari; Vivek K Bajpai
Journal:  Pharmacogn Mag       Date:  2013-10       Impact factor: 1.085

Review 8.  Phytochemical and Pharmacological Studies on the Genus Psoralea: A Mini Review.

Authors:  Cong-Cong Li; Teng-Long Wang; Zhong-Qun Zhang; Wen-Qiang Yang; Yue-Fei Wang; Xin Chai; Chun-Hua Wang; Zheng Li
Journal:  Evid Based Complement Alternat Med       Date:  2016-11-17       Impact factor: 2.629
  8 in total

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