Literature DB >> 17202503

Ex vivo simulation of drug action: quantification of drug-induced mRNA as a bridge between preclinical and clinical trials.

Masato Mitsuhashi.   

Abstract

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Year:  2007        PMID： 17202503     DOI： 10.1373/clinchem.2006.080473

Source DB:  PubMed          Journal:  Clin Chem        ISSN： 0009-9147            Impact factor:   8.327


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  3 in total

1.  cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis.

Authors:  Mark L Parrish; Chris Wright; Yarek Rivers; David Argilla; Heather Collins; Brendan Leeson; Andrey Loboda; Michael Nebozhyn; Matthew J Marton; Serguei Lejnine
Journal:  J Transl Med       Date:  2010-09-25       Impact factor: 5.531

2.  Trastuzumab-induced CCL20 and interleukin-8 mRNA in human whole blood ex vivo.

Authors:  Setsuo Hasegawa; Hideaki Kato; Hiroki Yamaguchi; Masafumi Yohda; Kazuhiko Obara; Hiroshi Izutsu; Mieko Ogura; Masato Mitsuhashi
Journal:  Invest New Drugs       Date:  2009-02-10       Impact factor: 3.850

3.  Ex vivo induction of mRNA in human whole blood as a new platform of drug and dietary supplement development.

Authors:  Masato Mitsuhashi; Mieko Ogura; Katsuya Endo; Kazuhiko Obara; Hiroshi Izutsu; Stephan R Targan; Motoko Maemura; Daisuke Tachikawa; Atsushi Shinagawa
Journal:  Pharm Res       Date:  2008-01-09       Impact factor: 4.200
  3 in total

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