Literature DB >> 17201022

What's in a number?

Jürgen Drews.   

Abstract

Ten years ago, the first estimates of the existing number of drug targets were made. This month's issue features an article and poster that together summarize current drug targets and associated characteristics, providing a basis to better understand the potential for future therapeutic exploitation.

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Year:  2006        PMID: 17201022     DOI: 10.1038/nrd2205

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  6 in total

Review 1.  PubChem as a public resource for drug discovery.

Authors:  Qingliang Li; Tiejun Cheng; Yanli Wang; Stephen H Bryant
Journal:  Drug Discov Today       Date:  2010-10-21       Impact factor: 7.851

2.  Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules.

Authors:  Warren R J D Galloway; Albert Isidro-Llobet; David R Spring
Journal:  Nat Commun       Date:  2010-09-21       Impact factor: 14.919

3.  Structural models in the assessment of protein druggability based on HTS data.

Authors:  Anvita Gupta; Arun Kumar Gupta; Kothandaraman Seshadri
Journal:  J Comput Aided Mol Des       Date:  2009-05-29       Impact factor: 3.686

4.  Study of polytopic membrane protein topological organization as a function of membrane lipid composition.

Authors:  Mikhail Bogdanov; Philip N Heacock; William Dowhan
Journal:  Methods Mol Biol       Date:  2010

Review 5.  Lipids in the assembly of membrane proteins and organization of protein supercomplexes: implications for lipid-linked disorders.

Authors:  Mikhail Bogdanov; Eugenia Mileykovskaya; William Dowhan
Journal:  Subcell Biochem       Date:  2008

6.  siRNA Genome Screening Approaches to Therapeutic Drug Repositioning.

Authors:  Olivia Perwitasari; Abhijeet Bakre; S Mark Tompkins; Ralph A Tripp
Journal:  Pharmaceuticals (Basel)       Date:  2013-01-28
  6 in total

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