Literature DB >> 17200494

Endurance training: an effective and safe treatment for patients with LGMD2I.

M-L Sveen1, T D Jeppesen, S Hauerslev, T O Krag, J Vissing.   

Abstract

We studied the effect of aerobic training on conditioning in patients with limb-girdle muscular dystrophy type 2I (LGMD2I). Nine patients with LGMD2I cycled fifty 30-minute sessions at 65% of their maximal oxygen uptake over 12 weeks. Training significantly improved work capacity, paralleled by self-reported improvements. Creatine kinase levels did not increase significantly, and muscle morphology was unaffected. Moderate-intensity endurance training is a safe method to increase exercise performance and daily function in patients with LGMD2I.

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Year:  2007        PMID： 17200494     DOI： 10.1212/01.wnl.0000250358.32199.24

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  28 in total

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