Literature DB >> 17199013

Currently available antiepileptic drugs.

Steven C Schachter1.   

Abstract

Many new antiepileptic drugs (AEDs) have become available over the past 15 years. At the same time, the emphasis on treating patients with epilepsy has grown from stopping seizures to avoiding side effects and maximizing quality of life. This review summarizes currently available AEDs, and presents general treatment principles and guidelines for AED selection. Unfortunately, despite the increased treatment options of today, seizure freedom without side effects remains unattainable for too many patients with epilepsy. Consequently, there remains a significant need for further development of new therapies.

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Year:  2007        PMID: 17199013     DOI: 10.1016/j.nurt.2006.11.005

Source DB:  PubMed          Journal:  Neurotherapeutics        ISSN: 1878-7479            Impact factor:   7.620


  74 in total

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Authors:  J I Isojärvi; E Taubøll; J S Tapanainen; A J Pakarinen; T J Laatikainen; M Knip; V V Myllylä
Journal:  Epilepsia       Date:  2001-03       Impact factor: 5.864

2.  The regulation of serum sodium after replacing carbamazepine with oxcarbazepine.

Authors:  J I Isojärvi; U E Huuskonen; A J Pakarinen; O Vuolteenaho; V V Myllylä
Journal:  Epilepsia       Date:  2001-06       Impact factor: 5.864

3.  Repeated neural tube defects and valproate monotherapy suggest a pharmacogenetic abnormality.

Authors:  S Duncan; S Mercho; I Lopes-Cendes; M H Seni; A Benjamin; F Dubeau; F Andermann; E Andermann
Journal:  Epilepsia       Date:  2001-06       Impact factor: 5.864

Review 4.  Pregabalin: a new anxiolytic.

Authors:  Bianca A Lauria-Horner; Robert B Pohl
Journal:  Expert Opin Investig Drugs       Date:  2003-04       Impact factor: 6.206

Review 5.  Some common issues in the use of antiepileptic drugs.

Authors:  Jorge J Asconapé
Journal:  Semin Neurol       Date:  2002-03       Impact factor: 3.420

Review 6.  Pharmacology and pharmacokinetics of fosphenytoin.

Authors:  T R Browne; A R Kugler; M A Eldon
Journal:  Neurology       Date:  1996-06       Impact factor: 9.910

Review 7.  Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience.

Authors:  Emilio Perucca
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

8.  Phenylethylmalonamide (PEMA). An important metabolite of primidone.

Authors:  I P Baumel; B B Gallagher; R H Mattson
Journal:  Arch Neurol       Date:  1972-07

9.  Seizures during barbiturate withdrawal: relation to blood level.

Authors:  W H Theodore; R J Porter; R F Raubertas
Journal:  Ann Neurol       Date:  1987-11       Impact factor: 10.422

Review 10.  Reproductive and metabolic disorders in women with epilepsy.

Authors:  Martha J Morrell
Journal:  Epilepsia       Date:  2003       Impact factor: 5.864

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  11 in total

1.  Novel therapeutic strategies for epilepsy--releasing the gene Genie.

Authors:  Graeme J Sills
Journal:  Epilepsy Curr       Date:  2009 Jan-Feb       Impact factor: 7.500

2.  Cannabidivarin is anticonvulsant in mouse and rat.

Authors:  A J Hill; M S Mercier; T D M Hill; S E Glyn; N A Jones; Y Yamasaki; T Futamura; M Duncan; C G Stott; G J Stephens; C M Williams; B J Whalley
Journal:  Br J Pharmacol       Date:  2012-12       Impact factor: 8.739

3.  Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism.

Authors:  T D M Hill; M-G Cascio; B Romano; M Duncan; R G Pertwee; C M Williams; B J Whalley; A J Hill
Journal:  Br J Pharmacol       Date:  2013-10       Impact factor: 8.739

4.  Anticonvulsant effects of leptin in epilepsy.

Authors:  Sabrina Diano; Tamas L Horvath
Journal:  J Clin Invest       Date:  2008-01       Impact factor: 14.808

Review 5.  Difficulties in Treatment and Management of Epilepsy and Challenges in New Drug Development.

Authors:  Abdul Wahab
Journal:  Pharmaceuticals (Basel)       Date:  2010-07-05

6.  Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility.

Authors:  Laith N Al-Eitan; Islam M Al-Dalalah; Hanan A Aljamal
Journal:  Saudi Pharm J       Date:  2019-04-24       Impact factor: 4.330

7.  Current trends in the treatment of infantile spasms.

Authors:  Chang-Yong Tsao
Journal:  Neuropsychiatr Dis Treat       Date:  2009-05-20       Impact factor: 2.570

8.  Levetiracetam in the treatment of epilepsy.

Authors:  Bassel Abou-Khalil
Journal:  Neuropsychiatr Dis Treat       Date:  2008-06       Impact factor: 2.570

9.  Reduction in mortality and teratogenicity following simultaneous administration of folic acid and vitamin E with antiepileptic, antihypertensive and anti-allergic drugs.

Authors:  Shahana Wahid; Rafeeq Alam Khan; Zeeshan Feroz
Journal:  J Pharm Bioallied Sci       Date:  2014-07

Review 10.  A systematic review of the effects of low-frequency repetitive transcranial magnetic stimulation on cognition.

Authors:  Claudia Lage; Katherine Wiles; Sukhwinder S Shergill; Derek K Tracy
Journal:  J Neural Transm (Vienna)       Date:  2016-08-08       Impact factor: 3.575

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