Literature DB >> 17197110

Autologous bone marrow transplantation/mobilization: a potential regenerative medicine for systemic degenerative disorders and healthy living.

Meenal Banerjee1, Ramesh R Bhonde.   

Abstract

Increased longevity is compromised for the quality of life due to prevalence of metabolic derangements and systemic degenerative disorders, as a result of lifestyle changes in modern days. In a craze to improve upon quality of life, use of pharmacological formulations aimed towards symptomatic treatment regimen is mandatory to manage variety of prevailing human ailments. However; these medicines have their own limitations and side effects, soliciting alternative therapy for better living. In light of preclinical and clinical studies on adult stem cells, bone marrow transplantation in healthy elderly individuals is likely to promote rejuvenation and prevent onset of degenerative disorders as well as cure prevailing disorders if any. Progress in unraveling pleuripotency of adult bone marrow stem cells compelled us to hypothesize that the only way to regain lost cells is to replace them with cells following the principle of 'Like begets Like' which may be achieved by autologous bone marrow transplantation/mobilization.

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Year:  2007        PMID: 17197110     DOI: 10.1016/j.mehy.2006.09.069

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  3 in total

1.  Bone regeneration at dental implant sites with suspended stem cells.

Authors:  R C Zheng; Y K Park; J J Cho; S K Kim; S J Heo; J Y Koak; J H Lee
Journal:  J Dent Res       Date:  2014-09-02       Impact factor: 6.116

2.  Reconstitution of marrow-derived extracellular matrix ex vivo: a robust culture system for expanding large-scale highly functional human mesenchymal stem cells.

Authors:  Yanlai Lai; Yun Sun; Charles M Skinner; Eugene L Son; Zhongding Lu; Rocky S Tuan; Robert L Jilka; Jian Ling; Xiao-Dong Chen
Journal:  Stem Cells Dev       Date:  2010-07       Impact factor: 3.272

3.  Direct lineage tracing reveals Activin-a potential for improved pancreatic homing of bone marrow mesenchymal stem cells and efficient ß-cell regeneration in vivo.

Authors:  Nidheesh Dadheech; Abhay Srivastava; Mitul Vakani; Paresh Shrimali; Ramesh Bhonde; Sarita Gupta
Journal:  Stem Cell Res Ther       Date:  2020-07-30       Impact factor: 6.832

  3 in total

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