Literature DB >> 17197054

The control of bone remodeling by neuropeptide Y receptors.

S J Allison1, P A Baldock, H Herzog.   

Abstract

An important role for the neuropeptide Y receptor system in the regulation of bone formation was recently revealed with a significant elevation in trabecular bone formation and bone volume following germline or hypothalamus-specific deletion of neuropeptide Y2 receptors in mice. Subsequent studies have now demonstrated that this central pathway is distinct from that of the other centrally regulated bone formation pathway mediated by leptin. This review discusses these recent findings and outlines how these new pathways could translate into potential novel targets for the treatment of bone disease.

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Year:  2006        PMID： 17197054     DOI： 10.1016/j.peptides.2006.05.029

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  9 in total

Review 1.  Roles of leptin in bone metabolism and bone diseases.

Authors:  Xu Xu Chen; Tianfu Yang
Journal:  J Bone Miner Metab       Date:  2015-03-18       Impact factor: 2.626

2.  Bone mass in Rett syndrome: association with clinical parameters and MECP2 mutations.

Authors:  Jay R Shapiro; Genila Bibat; Girish Hiremath; Mary E Blue; Shilpa Hundalani; Theodore Yablonski; Aditi Kantipuly; Charles Rohde; Michael Johnston; Sakkubai Naidu
Journal:  Pediatr Res       Date:  2010-11       Impact factor: 3.756

Review 3.  Endocrine regulation of bone and energy metabolism in hibernating mammals.

Authors:  Alison H Doherty; Gregory L Florant; Seth W Donahue
Journal:  Integr Comp Biol       Date:  2014-02-19       Impact factor: 3.326

4.  Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy.

Authors:  R Geoffrey Burwell; Ranjit K Aujla; Michael P Grevitt; Peter H Dangerfield; Alan Moulton; Tabitha L Randell; Susan I Anderson
Journal:  Scoliosis       Date:  2009-10-31

Review 5.  Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis.

Authors:  Lan-Juan Zhao; Hui Jiang; Christopher J Papasian; Dev Maulik; Betty Drees; James Hamilton; Hong-Wen Deng
Journal:  J Bone Miner Res       Date:  2008-01       Impact factor: 6.741

Review 6.  Leptin as an endocrine signal in bone.

Authors:  Nicola J Lee; Iris P L Wong; Paul A Baldock; Herbert Herzog
Journal:  Curr Osteoporos Rep       Date:  2008-06       Impact factor: 5.096

7.  Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.

Authors:  Weixin Xie; Fan Li; Yi Han; Yi Qin; Yuan Wang; Xiaoying Chi; Jie Xiao; Zhanchun Li
Journal:  Aging (Albany NY)       Date:  2020-05-07       Impact factor: 5.682

Review 8.  The role of GPCRs in bone diseases and dysfunctions.

Authors:  Jian Luo; Peng Sun; Stefan Siwko; Mingyao Liu; Jianru Xiao
Journal:  Bone Res       Date:  2019-07-08       Impact factor: 13.567

9.  Neuropeptide Y upregulates Runx2 and osterix and enhances osteogenesis in mouse MC3T3‑E1 cells via an autocrine mechanism.

Authors:  Bo Zhang; Xiaolei Zhang; Juan Xiao; Xuguang Zhou; Yuan Chen; Chunzheng Gao
Journal:  Mol Med Rep       Date:  2020-09-14       Impact factor: 2.952
  9 in total

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