Literature DB >> 17196911

Punctate midline myelotomy: a minimally invasive procedure for the treatment of pain in inextirpable abdominal and pelvic cancer.

Dun Hong1, Ake Andrén-Sandberg.   

Abstract

The midline of the dorsal column contains a pathway that may be more important for transmitting visceral nociceptive signals than the spinothalamic tract. Punctate midline myelotomy, a neuroablative operation with the intent of interrupting the midline of the dorsal column, has demonstrated efficacy in the treatment of otherwise intractable abdominal and pelvic cancer pain. The indications, technical procedure, outcomes, and complications of all published clinical studies of punctate midline myelotomy are reviewed. The lesion level of the spinal cord and the depth of the incision are discussed, with the focus on the feasibility of this technique.

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Year:  2007        PMID: 17196911     DOI: 10.1016/j.jpainsymman.2006.06.012

Source DB:  PubMed          Journal:  J Pain Symptom Manage        ISSN: 0885-3924            Impact factor:   3.612


  3 in total

Review 1.  Cortical and subcortical plasticity in the brains of humans, primates, and rats after damage to sensory afferents in the dorsal columns of the spinal cord.

Authors:  Jon H Kaas; Hui-Xin Qi; Mark J Burish; Omar A Gharbawie; Stephen M Onifer; James M Massey
Journal:  Exp Neurol       Date:  2007-07-06       Impact factor: 5.330

2.  Punctate Midline Myelotomy Reduces Pain Responses in a Rat Model of Lumbar Spine Pain: Evidence that the Postsynaptic Dorsal Column Pathway Conveys Pain from the Axial Spine.

Authors:  Haring J Nauta; Sabrina L McIlwrath; Karin N Westlund
Journal:  Cureus       Date:  2018-03-26

3.  Chronic opioid therapy and opioid tolerance: a new hypothesis.

Authors:  Joel S Goldberg
Journal:  Pain Res Treat       Date:  2013-01-14
  3 in total

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