| Literature DB >> 17194657 |
A Keijzer1, P van der Valk, G J Ossenkoppele, A A van de Loosdrecht.
Abstract
Accelerated programmed cell death or apoptosis appears to play an important role in the pathogenesis of myelodysplasia. As overexpression of TNF-alpha has been described to induce cell death in myelodysplasia, treatment with anti-TNF-alpha is currently being explored. Caution is needed because of an increased risk of opportunistic infection during anti-TNF-alpha treatment. We here describe a patient who was treated with anti-TNF-alpha for low risk myelodysplasia and died of invasive mucormycosis.Entities:
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Year: 2006 PMID： 17194657
Source DB: PubMed Journal: Haematologica ISSN： 0390-6078 Impact factor: 9.941