Literature DB >> 17193331

Benzophenanthridine alkaloids from Zanthoxylum nitidum (Roxb.) DC, and their analgesic and anti-inflammatory activities.

Jiang Hu1, Wei-Dong Zhang, Run-Hui Liu, Chuan Zhang, Yun-Heng Shen, Hui-Liang Li, Ming-Jin Liang, Xi-Ke Xu.   

Abstract

Seven benzophenanthridine alkaloids, 1-7, were isolated from the roots of Zanthoxylum nitidum. Among them, two novel alkaloids, named (R)-8-[(R)-1-hydroxyethyl]dihydrochelerythrine (1) and 8-methoxynorchelerythrine (2), were structurally identified as new compounds on the basis of the spectroscopic analysis. Bioactivity evaluation showed that nitidine (3), dihydrochelerythrine (4), oxyavicine (5), 8-methoxychelerythrine (6), and 8-hydroxydihydrochelerythrine (7) exhibit comparable analgesic and anti-inflammatory effects as hydrocortisone.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17193331     DOI： 10.1002/cbdv.200690108

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  15 in total

1.  Role of OCT2 and MATE1 in renal disposition and toxicity of nitidine chloride.

Authors:  L P Li; F F Song; Y Y Weng; X Yang; K Wang; H M Lei; J Ma; H Zhou; H D Jiang
Journal:  Br J Pharmacol       Date:  2016-07-09       Impact factor: 8.739

2.  Nitidine chloride inhibited the expression of S phase kinase-associated protein 2 in ovarian cancer cells.

Authors:  Huaping Mou; Ping Guo; Xiaoming Li; Chuanli Zhang; Jing Jiang; Lishuai Wang; Qiu Wang; Zhiping Yuan
Journal:  Cell Cycle       Date:  2017-06-08       Impact factor: 4.534

3.  Evaluation of Cytotoxic Activity Alkaloid Fractions of Zanthoxylum acanthopodium DC. Fruits.

Authors:  Dina Maya Syari; Rosidah Rosidah; Poppy Anjelisa Zaitun Hasibuan; Ginda Haro; Denny Satria
Journal:  Open Access Maced J Med Sci       Date:  2019-11-14

4.  Biological activities of nitidine, a potential anti-malarial lead compound.

Authors:  Jérome Bouquet; Marion Rivaud; Séverine Chevalley; Eric Deharo; Valérie Jullian; Alexis Valentin
Journal:  Malar J       Date:  2012-03-09       Impact factor: 2.979

5.  Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand.

Authors:  Katesarin Maneenoon; Chuanchom Khuniad; Yaowalak Teanuan; Nisachon Saedan; Supatra Prom-In; Nitiphol Rukleng; Watid Kongpool; Phongsura Pinsook; Winyu Wongwiwat
Journal:  J Ethnobiol Ethnomed       Date:  2015-05-30       Impact factor: 2.733

6.  Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways.

Authors:  Jiumao Lin; Aling Shen; Hongwei Chen; Jun Liao; Teng Xu; Liya Liu; Jing Lin; Jun Peng
Journal:  BMC Cancer       Date:  2014-09-30       Impact factor: 4.430

7.  (±)-Zanthonitidine A, a Pair of Enantiomeric Furoquinoline Alkaloids from Zanthoxylum nitidum with Antibacterial Activity.

Authors:  Li-Na Zhao; Xi-Xi Guo; Shuai Liu; Li Feng; Qi-Rui Bi; Zhe Wang; Ning-Hua Tan
Journal:  Nat Prod Bioprospect       Date:  2018-05-31

8.  Nitidine Chloride Inhibits SIN1 Expression in Osteosarcoma Cells.

Authors:  Hui Xu; Tong Cao; Xiaoqing Zhang; Ying Shi; Qing Zhang; Shuo Chai; Li Yu; Guoxi Jin; Jia Ma; Peter Wang; Yuyun Li
Journal:  Mol Ther Oncolytics       Date:  2019-02-05       Impact factor: 7.200

Review 9.  Natural products targeting cancer cell dependency.

Authors:  Changxiang Shi; Eun Ju Yang; Shishi Tao; Guowen Ren; Pui Kei Mou; Joong Sup Shim
Journal:  J Antibiot (Tokyo)       Date:  2021-06-23       Impact factor: 2.649

10.  Antimigration Activity of an Ethylacetate Fraction of Zanthoxylum acanthopodium DC. Fruits in 4T1 Breast Cancerzzm321990Cells

Authors:  Urip Harahap; Poppy Anjelisa Zaitun Hasibuan; Panal Sitorus; Nur Arfian; Denny Satria
Journal:  Asian Pac J Cancer Prev       Date:  2018-02-26
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.