Literature DB >> 17193224

The biochemistry of drug metabolism--an introduction: part 1. Principles and overview.

Bernard Testa1, Stefanie D Krämer.   

Abstract

Mesh：

Substances：

Year:  2006        PMID： 17193224     DOI： 10.1002/cbdv.200690111

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


× No keyword cloud information.
  14 in total

Review 1.  In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling.

Authors:  S Ekins; J Mestres; B Testa
Journal:  Br J Pharmacol       Date:  2007-06-04       Impact factor: 8.739

Review 2.  Predicting drug metabolism: experiment and/or computation?

Authors:  Johannes Kirchmair; Andreas H Göller; Dieter Lang; Jens Kunze; Bernard Testa; Ian D Wilson; Robert C Glen; Gisbert Schneider
Journal:  Nat Rev Drug Discov       Date:  2015-04-24       Impact factor: 84.694

3.  Homology modeling and metabolism prediction of human carboxylesterase-2 using docking analyses by GriDock: a parallelized tool based on AutoDock 4.0.

Authors:  Giulio Vistoli; Alessandro Pedretti; Angelica Mazzolari; Bernard Testa
Journal:  J Comput Aided Mol Des       Date:  2010-07-11       Impact factor: 3.686

4.  In Vitro Metabolism of Isopropylated and tert-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions.

Authors:  Allison L Phillips; Nicholas J Herkert; Jake C Ulrich; Jessica H Hartman; Matthew T Ruis; Ellen M Cooper; P Lee Ferguson; Heather M Stapleton
Journal:  Chem Res Toxicol       Date:  2020-03-18       Impact factor: 3.739

Review 5.  Overview of extracellular microvesicles in drug metabolism.

Authors:  Javier Conde-Vancells; Esperanza Gonzalez; Shelly C Lu; Jose M Mato; Juan M Falcon-Perez
Journal:  Expert Opin Drug Metab Toxicol       Date:  2010-05       Impact factor: 4.481

Review 6.  Application of Mathematical Modeling and Computational Tools in the Modern Drug Design and Development Process.

Authors:  Md Rifat Hasan; Ahad Amer Alsaiari; Burhan Zain Fakhurji; Mohammad Habibur Rahman Molla; Amer H Asseri; Md Afsar Ahmed Sumon; Moon Nyeo Park; Foysal Ahammad; Bonglee Kim
Journal:  Molecules       Date:  2022-06-29       Impact factor: 4.927

7.  Charged Tags for the Identification of Oxidative Drug Metabolites Based on Electrochemistry and Mass Spectrometry.

Authors:  Alexandra Gutmann; Lars Julian Wesenberg; Nadine Peez; Siegfried R Waldvogel; Thorsten Hoffmann
Journal:  ChemistryOpen       Date:  2020-05-06       Impact factor: 2.911

8.  Exploring the Metabolism of (+)-[18F]Flubatine in Vitro and in Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study.

Authors:  Friedrich-Alexander Ludwig; Steffen Fischer; René Smits; Winnie Deuther-Conrad; Alexander Hoepping; Solveig Tiepolt; Marianne Patt; Osama Sabri; Peter Brust
Journal:  Molecules       Date:  2018-02-20       Impact factor: 4.411

Review 9.  Metabolomics, a New Promising Technology for Toxicological Research.

Authors:  Kyu-Bong Kim; Byung Mu Lee
Journal:  Toxicol Res       Date:  2009-06-01

Review 10.  In silico pharmacology for drug discovery: applications to targets and beyond.

Authors:  S Ekins; J Mestres; B Testa
Journal:  Br J Pharmacol       Date:  2007-06-04       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.