Literature DB >> 17192812

Transcriptional regulation of Trk family neurotrophin receptors.

L Lei1, L F Parada.   

Abstract

The Trk family of neurotrophin receptors plays essential roles in cell fate specification, survival, growth, and differentiation. Their expression patterns are complex and dynamically regulated under many physiological and pathological conditions. However, the molecular mechanisms that control their tissue-specific expression are largely unknown. In this report, we review current knowledge about the transcriptional regulation of Trk receptors.

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Year:  2007        PMID: 17192812     DOI: 10.1007/s00018-006-6328-8

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN: 1420-682X            Impact factor:   9.261


  14 in total

1.  (R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.

Authors:  Ha-Soon Choi; Paul V Rucker; Zhicheng Wang; Yi Fan; Pamela Albaugh; Greg Chopiuk; Francois Gessier; Fangxian Sun; Francisco Adrian; Guoxun Liu; Tami Hood; Nanxin Li; Yong Jia; Jianwei Che; Susan McCormack; Allen Li; Jie Li; Auzon Steffy; AnneMarie Culazzo; Celine Tompkins; Van Phung; Andreas Kreusch; Min Lu; Bin Hu; Apurva Chaudhary; Mahavir Prashad; Tove Tuntland; Bo Liu; Jennifer Harris; H Martin Seidel; Jon Loren; Valentina Molteni
Journal:  ACS Med Chem Lett       Date:  2015-03-16       Impact factor: 4.345

Review 2.  A Slice of the Suicidal Brain: What Have Postmortem Molecular Studies Taught Us?

Authors:  Daniel Almeida; Gustavo Turecki
Journal:  Curr Psychiatry Rep       Date:  2016-11       Impact factor: 5.285

3.  Bex3 Dimerization Regulates NGF-Dependent Neuronal Survival and Differentiation by Enhancing trkA Gene Transcription.

Authors:  Laura Calvo; Begoña Anta; Saray López-Benito; Carlos Martín-Rodriguez; Francis S Lee; Pilar Pérez; Dionisio Martín-Zanca; Juan C Arévalo
Journal:  J Neurosci       Date:  2015-05-06       Impact factor: 6.167

4.  Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models.

Authors:  Pam Albaugh; Yi Fan; Yuan Mi; Fangxian Sun; Francisco Adrian; Nanxin Li; Yong Jia; Yelena Sarkisova; Andreas Kreusch; Tami Hood; Min Lu; Guoxun Liu; Shenlin Huang; Zuosheng Liu; Jon Loren; Tove Tuntland; Donald S Karanewsky; H Martin Seidel; Valentina Molteni
Journal:  ACS Med Chem Lett       Date:  2012-01-01       Impact factor: 4.345

5.  p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes.

Authors:  F Truzzi; A Marconi; P Atzei; M C Panza; R Lotti; K Dallaglio; R Tiberio; E Palazzo; C Vaschieri; C Pincelli
Journal:  Cell Death Differ       Date:  2010-12-10       Impact factor: 15.828

6.  Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.

Authors:  Min Zou; Shengguo Li; William H Klein; Mengqing Xiang
Journal:  Dev Biol       Date:  2012-02-03       Impact factor: 3.582

7.  Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17.

Authors:  Anjali G Shah; Meyer J Friedman; Shanshan Huang; Meredith Roberts; Xiao-Jiang Li; Shihua Li
Journal:  Hum Mol Genet       Date:  2009-07-30       Impact factor: 6.150

8.  Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide.

Authors:  Yogesh Dwivedi; Hooriyah S Rizavi; Hui Zhang; Amal C Mondal; Rosalinda C Roberts; Robert R Conley; Ghanshyam N Pandey
Journal:  Biol Psychiatry       Date:  2008-10-19       Impact factor: 13.382

9.  Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathways.

Authors:  Neus Pedraza; Marta Rafel; Isis Navarro; Mario Encinas; Martí Aldea; Carme Gallego
Journal:  J Biol Chem       Date:  2009-09-28       Impact factor: 5.157

Review 10.  Natural Products for Neurodegeneration: Regulating Neurotrophic Signals.

Authors:  Md Sahab Uddin; Abdullah Al Mamun; Md Motiar Rahman; Philippe Jeandet; Athanasios Alexiou; Tapan Behl; Md Shahid Sarwar; Eduardo Sobarzo-Sánchez; Ghulam Md Ashraf; Amany A Sayed; Ghadeer M Albadrani; Ilaria Peluso; Mohamed M Abdel-Daim
Journal:  Oxid Med Cell Longev       Date:  2021-06-21       Impact factor: 6.543

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