| Literature DB >> 17192 |
H Rodt, B Netzel, D Niethammer, M Körbling, D Götze, H J Kolb, E Thiel, R J Haas, T M Fliedner, S Thierfelder.
Abstract
The experimental data show that absorption of ATG with liver-kidney homogenate and CLL and LCL cells stepwise removed the hemopoietic toxicity, whereas the specific activity against T lymphocytes remained. Although the mode of action of absorbed ATG could not be tested in the first clinical case, the successful experiments in rodents together with the fact that the incubation treatment was tolerated by the patient may provide a new way of preventing fatal GVH reactions in man.Entities:
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Year: 1977 PMID： 17192
Source DB: PubMed Journal: Transplant Proc ISSN： 0041-1345 Impact factor: 1.066