Literature DB >> 17191680

Yaequinolones, new insecticidal antibiotics produced by Penicillium sp. FKI-2140. I. Taxonomy, fermentation, isolation and biological activity.

Ryuji Uchida1, Rie Imasato, Yuichi Yamaguchi, Rokuro Masuma, Kazuro Shiomi, Hiroshi Tomoda, Satoshi Omura.   

Abstract

New nine insecticidal antibiotics designated yaequinolones were isolated from the culture broth of the fungal strain Penicillium sp. FKI-2140 by solvent extraction, centrifugal partition chromatography and HPLC. Yaequinolones showed growth inhibitory activity against brine shrimp (Artemia salina). Among them, yaequinolone F has the most potent activity with MIC value of 0.19 microg/ml.

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Year:  2006        PMID： 17191680     DOI： 10.1038/ja.2006.86

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  4 in total

Review 1.  Oxidative Cyclization in Natural Product Biosynthesis.

Authors:  Man-Cheng Tang; Yi Zou; Kenji Watanabe; Christopher T Walsh; Yi Tang
Journal:  Chem Rev       Date:  2016-12-12       Impact factor: 60.622

2.  Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids.

Authors:  Yi Zou; Zhajun Zhan; Dehai Li; Mancheng Tang; Ralph A Cacho; Kenji Watanabe; Yi Tang
Journal:  J Am Chem Soc       Date:  2015-04-14       Impact factor: 15.419

3.  Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ.

Authors:  Sophie L Mader; Alois Bräuer; Michael Groll; Ville R I Kaila
Journal:  Nat Commun       Date:  2018-03-21       Impact factor: 14.919

4.  Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis.

Authors:  Yi Zou; Marc Garcia-Borràs; Mancheng C Tang; Yuichiro Hirayama; Dehai H Li; Li Li; Kenji Watanabe; K N Houk; Yi Tang
Journal:  Nat Chem Biol       Date:  2017-01-23       Impact factor: 15.040
  4 in total

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