Literature DB >> 17191679

Talosins A and B: new isoflavonol glycosides with potent antifungal activity from Kitasatospora kifunensis MJM341. II. Physicochemical properties and structure determination.

Won-Gon Kim1, Tae Mi Yoon, Hyung Jin Kwon, Joo Won Suh.   

Abstract

In our screening program for new antifungal agents from microbial secondary metabolites, two new isoflavonol glycosides, with potent antifungal activity, talosins A and B, were isolated from the culture broth of Kitasatospora kifunensis MJM341. Talosins A and B were determined to be genistein 7-alpha-L-6-deoxy-talopyranoside and genistein 4',7-di-alpha-L-6-deoxy-talopyranoside, respectively, by spectroscopic studies. They are the first flavonoid glycosides incorporating 6-deoxy-talose as a sugar component.

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Year:  2006        PMID: 17191679     DOI: 10.1038/ja.2006.85

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  7 in total

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Review 2.  Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites.

Authors:  Brett C Covington; John A McLean; Brian O Bachmann
Journal:  Nat Prod Rep       Date:  2017-01-04       Impact factor: 13.423

3.  Two-step enzymatic synthesis of 6-deoxy-L-psicose.

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Journal:  Tetrahedron Lett       Date:  2016-07-06       Impact factor: 2.415

4.  Improvement of the productivity of ecumicin, a novel anti-tuberculosis agent, from new Nonomuraea sp. MJM5123.

Authors:  Ying-Yu Jin; Jin-Yong Kim; Seung Hwan Yang; Hanki Lee; Joo-Won Suh
Journal:  J Antibiot (Tokyo)       Date:  2015-12-09       Impact factor: 2.649

5.  In vivo metabolism of Talosin A, new isoflavonol glycoside from Kitasatospora kifunensis, in rats.

Authors:  Jong-Hwan Lim; In-Bae Song; Youn-Hwan Hwang; Myoung-Seok Kim; Jong-Woo Kim; Jin-Yong Kim; Joo Won Suh; Hyo-In Yun
Journal:  J Vet Sci       Date:  2011-06       Impact factor: 1.672

6.  Chemical Identification of Isoflavonoids from a Termite-Associated Streptomyces sp. RB1 and Their Neuroprotective Effects in Murine Hippocampal HT22 Cell Line.

Authors:  Seoung Rak Lee; Ji Hoon Song; Jae-Hyoung Song; Hyun-Jeong Ko; Ji Yun Baek; Tuy An Trinh; Christine Beemelmanns; Noriko Yamabe; Ki Hyun Kim
Journal:  Int J Mol Sci       Date:  2018-09-06       Impact factor: 5.923

7.  Poly(chitosan-ester-ether-urethane) Hydrogels as Highly Controlled Genistein Release Systems.

Authors:  Martyna Zagórska-Dziok; Patrycja Kleczkowska; Ewa Olędzka; Ramona Figat; Marcin Sobczak
Journal:  Int J Mol Sci       Date:  2021-03-24       Impact factor: 5.923

  7 in total

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