| Literature DB >> 17190593 |
Abstract
A new report (Szutorisz et al., 2006) suggests that embryonic stem (ES) cells adopt an unusual strategy to remain perpetually poised for differentiation. Apparently, ES cells use the proteasome to target transcriptional preinitiation complexes, thus minimizing transcriptional noise at genes that promote differentiation.Mesh:
Substances:
Year: 2006 PMID: 17190593 DOI: 10.1016/j.cell.2006.12.011
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582