OBJECTIVE: Behçet's disease (BD) is a multisystemic inflammatory disorder associated with high levels of depressive symptoms and lower quality of life (QoL). In this study, we aimed to investigate the impact of major depression (MD) on the QoL of patients with BD. METHOD: BD outpatients (n=25) and psychiatric outpatients (n=25) with only MD among the Axis I psychiatric disorders, and BD outpatients (n=25) and healthy controls (n=25) without any Axis I psychiatric disorder were included in the study. The Structured Clinical Interview for DSM-IV (SCID-I) was used to determine Axis I psychiatric disorders. Depression and QoL levels were assessed with the Beck Depression Inventory (BDI) and the World Health Organization QoL Assessment-Brief (WHOQOL-BREF), respectively. RESULTS: There was no significant difference with regard to demographic characteristics between the groups. Psychiatric and BD patients with MD had significantly lower overall WHOQOL-BREF subscale scores than BD patients without MD and healthy controls. No significant difference was found in terms of QoL between the groups of psychiatric and BD patients with MD, nor between the groups of BD patients without MD and healthy controls. Overall, there was a significantly negative correlation between all WHOQOL-BREF subscale and BDI scores in BD patients. CONCLUSION: The study suggests that concurrent MD has a negative impact on QoL of BD patients and that QoL is negatively correlated with the severity of depressive symptoms.
OBJECTIVE: Behçet's disease (BD) is a multisystemic inflammatory disorder associated with high levels of depressive symptoms and lower quality of life (QoL). In this study, we aimed to investigate the impact of major depression (MD) on the QoL of patients with BD. METHOD:BD outpatients (n=25) and psychiatric outpatients (n=25) with only MD among the Axis I psychiatric disorders, and BD outpatients (n=25) and healthy controls (n=25) without any Axis I psychiatric disorder were included in the study. The Structured Clinical Interview for DSM-IV (SCID-I) was used to determine Axis I psychiatric disorders. Depression and QoL levels were assessed with the Beck Depression Inventory (BDI) and the World Health Organization QoL Assessment-Brief (WHOQOL-BREF), respectively. RESULTS: There was no significant difference with regard to demographic characteristics between the groups. Psychiatric and BDpatients with MD had significantly lower overall WHOQOL-BREF subscale scores than BDpatients without MD and healthy controls. No significant difference was found in terms of QoL between the groups of psychiatric and BDpatients with MD, nor between the groups of BDpatients without MD and healthy controls. Overall, there was a significantly negative correlation between all WHOQOL-BREF subscale and BDI scores in BDpatients. CONCLUSION: The study suggests that concurrent MD has a negative impact on QoL of BDpatients and that QoL is negatively correlated with the severity of depressive symptoms.
Authors: Claudia Fabiani; Antonio Vitale; Ida Orlando; Jurgen Sota; Marco Capozzoli; Rossella Franceschini; Mauro Galeazzi; Gian Marco Tosi; Bruno Frediani; Luca Cantarini Journal: Intern Emerg Med Date: 2017-06-15 Impact factor: 3.397
Authors: Hania Zayed; Dina Effat; Zeinab Nawito; Amany Ahmed Abdou; Mohamed Nasr El Din; Sherif El-Refaei; Mahasen Amin; Yasser Mohamed; Amr Amin; Ahmed Wafie; Khaled Abu El-Einin Journal: Clin Rheumatol Date: 2011-03-08 Impact factor: 2.980