| Literature DB >> 17189684 |
Veljko Veljkovic1, Jean-François Mouscadet, Nevena Veljkovic, Sanja Glisic, Zeger Debyser.
Abstract
Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity.Entities:
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Year: 2006 PMID: 17189684 DOI: 10.1016/j.bmcl.2006.12.029
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823