Literature DB >> 17189199

The "domino theory" of hunger: the hypothalamus is hot.

Charles V Mobbs1.   

Abstract

Mechanisms by which the hypothalamus senses nutritional status are important for many metabolic diseases, including obesity and diabetes. Now, report that hypothalamic neurons sense nutritional deficit through a cascade of events involving leptin, corticosterone, and glial production of thyroid hormone, leading to neuronal induction of uncoupling protein.

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Year:  2007        PMID： 17189199     DOI： 10.1016/j.cmet.2006.12.005

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  3 in total

1.  Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance.

Authors:  Guo Zhang; Hua Bai; Hai Zhang; Camin Dean; Qiang Wu; Juxue Li; Sara Guariglia; Qingyuan Meng; Dongsheng Cai
Journal:  Neuron       Date:  2011-02-10       Impact factor: 17.173

2.  Blood profile of proteins and steroid hormones predicts weight change after weight loss with interactions of dietary protein level and glycemic index.

Authors:  Ping Wang; Claus Holst; Malene R Andersen; Arne Astrup; Freek G Bouwman; Sanne van Otterdijk; Will K W H Wodzig; Marleen A van Baak; Thomas M Larsen; Susan A Jebb; Anthony Kafatos; Andreas F H Pfeiffer; J Alfredo Martinez; Teodora Handjieva-Darlenska; Marie Kunesova; Wim H M Saris; Edwin C M Mariman
Journal:  PLoS One       Date:  2011-02-14       Impact factor: 3.240

3.  Stanniocalcin2 acts as an anorectic factor through activation of STAT3 pathway.

Authors:  Yang Jiao; Jiejie Zhao; Guojun Shi; Xing Liu; Xuelian Xiong; Xiaoying Li; Huijie Zhang; Qinyun Ma; Yan Lu
Journal:  Oncotarget       Date:  2017-07-20
  3 in total

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