Literature DB >> 17187263

[Advances in cardiovascular medicine through molecular imaging].

M Nahrendorf1, R Weissleder.   

Abstract

We will witness a change of paradigm in cardiovascular imaging, which is empowered by advances in imaging technology, biochemistry, molecular biology and nanotechnology. Instead of simply following the physical distribution of established contrast agents, we now have the opportunity to noninvasively image biological processes such as enzyme activity, interaction with cell surface markers, gene expression and cell migration. These advancements open up new avenues in basic cardiovascular research and will greatly speed up the pace of discovery. Patient management will profit as well: cardiovascular molecular imaging will strengthen personlized and prophylactic medicine through timely and precise diagnostics. In our review we describe selected molecular imaging strategies in atherosclerosis, myocardial ischemia and healing.

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Year:  2007        PMID: 17187263     DOI: 10.1007/s00117-006-1450-z

Source DB:  PubMed          Journal:  Radiologe        ISSN: 0033-832X            Impact factor:   0.635


  54 in total

1.  Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death.

Authors:  F D Kolodgie; J Narula; A P Burke; N Haider; A Farb; Y Hui-Liang; J Smialek; R Virmani
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

2.  Noninvasive detection of plaque instability with use of radiolabeled annexin A5 in patients with carotid-artery atherosclerosis.

Authors:  Bas L J H Kietselaer; Chris P M Reutelingsperger; Guido A K Heidendal; Mat J A P Daemen; Werner H Mess; Leonard Hofstra; Jagat Narula
Journal:  N Engl J Med       Date:  2004-04-01       Impact factor: 91.245

3.  Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction.

Authors:  Jiqiu Chen; Ching-Hsuan Tung; Jennifer R Allport; Si Chen; Ralph Weissleder; Paul L Huang
Journal:  Circulation       Date:  2005-04-04       Impact factor: 29.690

4.  Molecular imaging in cancer.

Authors:  Ralph Weissleder
Journal:  Science       Date:  2006-05-26       Impact factor: 47.728

5.  Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction.

Authors:  Matthias Nahrendorf; Kai Hu; Stefan Frantz; Farouc A Jaffer; Ching-Hsuan Tung; Karl-Heinz Hiller; Sabine Voll; Peter Nordbeck; David Sosnovik; Stefan Gattenlöhner; Mikhail Novikov; Gerhard Dickneite; Guy L Reed; Peter Jakob; Anthony Rosenzweig; Wolfgang R Bauer; Ralph Weissleder; Georg Ertl
Journal:  Circulation       Date:  2006-02-27       Impact factor: 29.690

6.  Monitoring of bone marrow cell homing into the infarcted human myocardium.

Authors:  Michael Hofmann; Kai C Wollert; Gerd P Meyer; Alix Menke; Lubomir Arseniev; Bernd Hertenstein; Arnold Ganser; Wolfram H Knapp; Helmut Drexler
Journal:  Circulation       Date:  2005-04-25       Impact factor: 29.690

7.  Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.

Authors:  Matthias Nahrendorf; Farouc A Jaffer; Kimberly A Kelly; David E Sosnovik; Elena Aikawa; Peter Libby; Ralph Weissleder
Journal:  Circulation       Date:  2006-09-25       Impact factor: 29.690

8.  Superparamagnetic iron oxide-enhanced MRI of atherosclerotic plaques in Watanabe hereditable hyperlipidemic rabbits.

Authors:  S A Schmitz; S E Coupland; R Gust; S Winterhalter; S Wagner; M Kresse; W Semmler; K J Wolf
Journal:  Invest Radiol       Date:  2000-08       Impact factor: 6.016

9.  Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction.

Authors:  David F Meoli; Mehran M Sadeghi; Svetlana Krassilnikova; Brian N Bourke; Frank J Giordano; Donald P Dione; Haili Su; D Scott Edwards; Shuang Liu; Thomas D Harris; Joseph A Madri; Barry L Zaret; Albert J Sinusas
Journal:  J Clin Invest       Date:  2004-06       Impact factor: 14.808

10.  In vivo imaging of proteolytic activity in atherosclerosis.

Authors:  Jiqiu Chen; Ching-Hsuan Tung; Umar Mahmood; Vasilis Ntziachristos; Robert Gyurko; Mark C Fishman; Paul L Huang; Ralph Weissleder
Journal:  Circulation       Date:  2002-06-11       Impact factor: 29.690

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  2 in total

1.  Glycolaldehyde and maleyl conjugated human serum albumin as potential macrophage-targeting carriers for molecular imaging purposes.

Authors:  Björn Gustafsson; Ulf Hedin; Kenneth Caidahl
Journal:  Contrast Media Mol Imaging       Date:  2014-04-22       Impact factor: 3.161

2.  Cellular Uptake of Plain and SPION-Modified Microbubbles for Potential Use in Molecular Imaging.

Authors:  Mona Ahmed; Barbara Cerroni; Anton Razuvaev; Johan Härmark; Gaio Paradossi; Kenneth Caidahl; Björn Gustafsson
Journal:  Cell Mol Bioeng       Date:  2017-08-10       Impact factor: 2.321

  2 in total

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