Central and peripheral thermoreceptors. Comparative analysis of the effects of prolonged adaptation to cold and noradrenaline.

This report presents results obtained from many years of study of the effects of prolonged adaptation to cold and noradrenaline on the spike activity of central hypothalamic and peripheral skin thermoreceptors. The involvement of the sympathetic nervous system in forming adaptive changes in the regulatory characteristics of temperature homeostasis and the significance of the various components of thermoreceptor activity to the formation of effector responses are discussed. The roles of different groups of thermoreceptors in forming temperature sensations are analyzed.